Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.35 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
| ▸ | MMP16 | P51512 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14890392 | 1.00 | TP53 (0.40) | TP53SLC7A5ADAMTS4DPP4DPP8 | |
| SCHEMBL214942 | 1.00 | TP53 (0.40) | TP53SLC7A5ADAMTS4DPP4DPP8 | |
| SCHEMBL18921013 | 1.00 | TP53 (0.40) | TP53SLC7A5ADAMTS4DPP4DPP8 | |
| Valine SCHEMBL18000820 | 0.86 | SLC7A5 (0.65) | TP53SLC7A5ADAMTS4DPP4DPP8 | |
| SCHEMBL26449009 | 0.81 | TP53 (0.41) | TP53SLC7A5ADAMTS4 | |
| SCHEMBL26449008 | 0.81 | TP53 (0.41) | TP53SLC7A5ADAMTS4 | |
| SCHEMBL4300140 | 0.80 | SLC7A5 (0.43) | TP53SLC7A5ADAMTS4GABRR1MMP2 | |
| SCHEMBL196164 | 0.80 | TP53 (0.45) | TP53SLC7A5ADAMTS4 | |
| SCHEMBL7424097 | 0.80 | TP53 (0.45) | TP53SLC7A5ADAMTS4 | |
| SCHEMBL196163 | 0.80 | TP53 (0.45) | TP53SLC7A5ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 758 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113491776-B | Anti-CD 269 antibody-drug conjugate (ADC), anti-CD 269 antibody and uses thereof | 马克思-德布鲁克-分子医学中心亥姆霍兹联合会 | 2025-01-21 | — | — | CN | claimed |
| WO-2024178139-A1 | COMPOSITIONS AND METHODS FOR TARGETING TUMOR-ASSOCIATED MACROPHAGES | RESOLUTE SCIENCE, INC. (US) | 2024-08-29 | — | — | WO | claimed |
| WO-2024178140-A1 | COMPOSITIONS AND METHODS FOR TARGETING TUMOR-ASSOCIATED MACROPHAGES | RESOLUTE SCIENCE, INC. (US) | 2024-08-29 | — | — | WO | claimed |
| CN-117881394-A | Pharmaceutical composition and oral dosage form of ketamine derivative | 凯瑞康宁生物工程（武汉）有限公司 | 2024-04-12 | — | — | CN | claimed |
| US-20240036055-A1 | Multiplexed DiLeu-Biotin-Azide (DBA) Tag Enabled Isobaric Tandem Orthogonal Proteolysis Activity-Based Protein Profiling (isoBOP-ABPP) Platform For High-Throughput Quantitative Pan-PTM Analysis | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2024-02-01 | — | — | US | claimed |
| CN-116981450-A | Combination of antidepressants and dextromethorphan for the treatment of neuropsychiatric disorders | 安泰赛普生物风投二代有限责任公司 | 2023-10-31 | — | — | CN | claimed |
| CN-111836798-B | Prodrugs of ketamine, compositions and uses thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2022-04-15 | — | — | CN | claimed |
| CN-112321490-A | Auxiliary agent and preparation method thereof | 宿迁联盛科技股份有限公司 | 2021-02-05 | — | — | CN | claimed |
| CN-112135812-A | Ketamine derivatives and pharmaceutical compositions thereof | 凯瑞康宁生物工程（武汉）有限公司 | 2020-12-25 | — | — | CN | claimed |
| US-10414822-B2 | Cytotoxic and anti-mitotic compounds, and methods of using the same | ZYMEWORKS INC. (CA) | 2019-09-17 | — | — | US | claimed |
| US-8034780-B2 | Isolation, purification, and structure elucidation of the antiproliferative compound coibamide A | SMITHSONIAN TROPICAL RESEARCH INSTITUTE | 2011-10-11 | — | — | US | claimed |
| WO-2011033296-A1 | PRODRUGS OF GUANFACINE | SHIRE LLC (US) | 2011-03-24 | — | — | WO | claimed |
| US-20110065796-A1 | PRODRUGS OF GUANFACINE | SHIRE LLC (US) | 2011-03-17 | — | — | US | claimed |
| CN-100532381-C | Antineoplastic compound, medicament composition and use thereof | JIANMIN WANG (CN) | 2009-08-26 | — | — | CN | claimed |
| CN-101475565-A | Anti-hypertension compound, and preparation, pharmaceutical composition and use thereof | JIANMIN WANG (CN) | 2009-07-08 | — | — | CN | claimed |
| US-20090023642-A1 | Isolation, Purification, and Structure Elucidation of the Antiproliferative Compound Coibamide A | THE STATE OF OREGON, ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY | 2009-01-22 | — | — | US | claimed |
| CN-101314600-A | Antineoplastic compound, medicament composition and use thereof | JIANMIN WANG (CN) | 2008-12-03 | — | — | CN | claimed |
| EP-1049481-B1 | SYNTHETIC ANTINEOPLASTIC AGENTS DERIVED FROM DOLASTATIN 15 AND METHODS OF MAKING SAME | UNIV ARIZONA (US) | 2005-04-20 | — | — | EP | claimed |
| EP-0842142-B1 | PROCESS FOR PRODUCING ALPHA-(N,N DIALKYL)-AMINO CARBOXYLIC ACID AMIDES | BASF AG (DE) | 2001-09-26 | — | — | EP | claimed |
| US-5945543-A | REACTING CORRESPONDING FREE ACIDS WITH PRIMARY OR SECONDARY AMINES IN THE PRESENCE OF ANHYDRIDES OF AN ALKANEPHOSPHONIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023642-A1 | Isolation, Purification, and Structure Elucidation of the Antiproliferative Compound Coibamide A | TOP2B, MCL1, MKI67 | TP53 166/4885SLC7A5 1596/4885ADAMTS4 2926/4885 |
| US-10414822-B2 | Cytotoxic and anti-mitotic compounds, and methods of using the same | CCNB1, PLK1, BOD1L1 | TP53 55/4885SLC7A5 3475/4885ADAMTS4 3349/4885 |
| US-20110065796-A1 | PRODRUGS OF GUANFACINE | DNPEP, VIP, GDA | TP53 4233/4885SLC7A5 121/4885ADAMTS4 1110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.