SCHEMBL196164

SCHEMBL196164

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nearest known ligand 0.45

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.45
TSHR P16473 1/20 0.33
SLC7A5 Q01650 1/20 0.32
ADAMTS4 O75173 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7424097 1.00 TP53 (0.45) TP53TSHRSLC7A5ADAMTS4
SCHEMBL196163 1.00 TP53 (0.45) TP53TSHRSLC7A5ADAMTS4
Hydrochloric Acid SCHEMBL32661867 0.97 TP53 (0.43) TP53TSHRSLC7A5ADAMTS4
SCHEMBL28001459 0.81 TP53 (0.43) TP53TSHRSLC7A5ADAMTS4
SCHEMBL18921013 0.80 TP53 (0.40) TP53SLC7A5ADAMTS4
SCHEMBL14890392 0.80 TP53 (0.40) TP53SLC7A5ADAMTS4
SCHEMBL214942 0.80 TP53 (0.40) TP53SLC7A5ADAMTS4
SCHEMBL15023 0.80 TP53 (0.40) TP53SLC7A5ADAMTS4
SCHEMBL22383998 0.79 TP53 (0.41) TP53TSHRADAMTS4
SCHEMBL26449008 0.79 TP53 (0.41) TP53TSHRSLC7A5ADAMTS4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160244484-A1 ANTI-INFLAMMATORY TRIPEPTIDES DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2016-08-25 US claimed
EP-3049428-A1 ANTI-INFLAMMATORY TRIPEPTIDES Dr. August Wolff GmbH & Co. KG Arzneimittel (DE) 2016-08-03 EP claimed
WO-2015040235-A1 ANTI-INFLAMMATORY TRIPEPTIDES DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL (DE) 2015-03-26 WO claimed
US-12448383-B2 Compounds and methods for treatment of viral infections GILEAD SCIENCES, INC. (US) 2025-10-21 US disclosed
US-20240246986-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. 2024-07-25 US disclosed
US-20240150359-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. 2024-05-09 US disclosed
US-11845755-B2 Compounds and methods for treatment of viral infections GILEAD SCIENCES, INC. (US) 2023-12-19 US disclosed
US-11780844-B2 Compounds and methods for treatment of viral infections GILEAD SCIENCES, INC. (US) 2023-10-10 US disclosed
US-11780844-B2 Compounds and methods for treatment of viral infections GILEAD SCIENCES, INC. (US) 2023-10-10 US disclosed
US-11780844-B2 Compounds and methods for treatment of viral infections GILEAD SCIENCES, INC. (US) 2023-10-10 US disclosed
US-20230279014-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS GILEAD SCIENCES, INC. 2023-09-07 US disclosed
US-5898029-A PROMOTING SENSITIVITY OF NEURONAL CELL SYSTEMS TO NEUROTROPHIC FACTORS BY THE IMMUNOPHILIN LIGANDS FOR THERAPEUTIC APPLICATION IN DISEASES INVOLVING NEURAL DEGENERATION, NERVE DAMAGE BY PHYSICAL INJURY THE JOHN HOPKINS UNIVERSITY (US) 1999-04-27 US disclosed
WO-1998046247-A1 SOLID PHASE SYNTHESIS OF IMMUNOSUPPRESSIVE AGENTS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1998-10-22 WO disclosed
WO-1998011908-A1 COMBINATION THERAPY FOR TREATMENT OF ARTHRITIC DISEASES BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-03-26 WO disclosed
CN-1152941-A Genes for synthesizing antipathogenic substances CIBA GEIGY AG (CH) 1997-06-25 CN disclosed
EP-0094412-B1 MEDICAL PROCESS AND PREPARATION JOHNSTON, Frederick Bertram (US) 1987-07-22 EP disclosed
EP-0094412-A4 MEDICAL PROCESS AND PREPARATION. JOHNSTON FREDERICK BERTRAM 1984-04-24 EP disclosed
EP-0094412-A1 MEDICAL PROCESS AND PREPARATION. JOHNSTON FREDERICK BERTRAM 1983-11-23 EP disclosed
WO-1983001725-A1 MEDICAL PROCESS AND PREPARATION JOHNSTON, FREDERICK, BERTRAM 1983-05-26 WO disclosed
US-4362745-A Medical process and preparation JOHNSTON FREDERICK B 1982-12-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11780844-B2 Compounds and methods for treatment of viral infections HAVCR2, EIF2AK2, OAT TP53 186/4885TSHR 4522/4885SLC7A5 2807/4885
US-20240150359-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS HAVCR2, EIF2AK2, OAT TP53 186/4885TSHR 4522/4885SLC7A5 2807/4885
US-20230279014-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS HAVCR2, EIF2AK2, OAT TP53 186/4885TSHR 4522/4885SLC7A5 2807/4885
US-20160244484-A1 ANTI-INFLAMMATORY TRIPEPTIDES VIP, TNF, ENPEP TP53 4487/4885TSHR 2489/4885SLC7A5 1859/4885
US-20240246986-A1 COMPOUNDS AND METHODS FOR TREATMENT OF VIRAL INFECTIONS HAVCR2, EIF2AK2, OAT TP53 186/4885TSHR 4522/4885SLC7A5 2807/4885
US-12448383-B2 Compounds and methods for treatment of viral infections HAVCR2, EIF2AK2, OAT TP53 186/4885TSHR 4522/4885SLC7A5 2807/4885
US-11845755-B2 Compounds and methods for treatment of viral infections HAVCR2, EIF2AK2, OAT TP53 186/4885TSHR 4522/4885SLC7A5 2807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.