Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 11/20 | 0.35 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.35 |
| ▸ | FAP | Q12884 | 7/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.35 |
| ▸ | PREP | P48147 | 3/20 | 0.35 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | CTSH | P09668 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 4/20 | 0.32 |
| ▸ | REN | P00797 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PEPD | P12955 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15024154 | 0.87 | ACE (0.36) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL10056862 | 0.69 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL23794392 | 0.69 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL14865113 | 0.69 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL10056861 | 0.68 | DPP4 (0.58) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL12285674 | 0.68 | DPP4 (0.58) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL10770001 | 0.67 | HSD17B10 (0.33) | LMNAHSD17B10 | |
| SCHEMBL57300 | 0.66 | ACE (0.38) | RAB9AACERENKDM4EF2 | |
| SCHEMBL16000536 | 0.66 | ACE (0.38) | RAB9AACERENKDM4EF2 | |
| SCHEMBL13233696 | 0.66 | ACE (0.38) | RAB9AACERENKDM4EF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029567-B2 | Hypoglycemic compounds | CADILA PHARMACEUTICALS LIMITED (IN) | 2015-05-12 | — | — | US | disclosed |
| US-20130150578-A1 | NOVEL HYPOGLYCEMIC COMPOUNDS | CADILA PHARMACEUTICALS LIMITED (IN) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150578-A1 | NOVEL HYPOGLYCEMIC COMPOUNDS | GLP1R, GPR119, IAPP | DPP4 10/4885DPP7 14/4885FAP 2786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.