Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15009016 | 1.00 | BCHE (0.52) | BCHEMAOBMAOAKMT2ASMN1; SMN2 | |
| SCHEMBL12500125 | 0.85 | ALOX5 (0.56) | BCHEMAOBMAOAKMT2ASMN1; SMN2 | |
| SCHEMBL16871388 | 0.85 | ALOX5 (0.56) | BCHEMAOBMAOAKMT2ASMN1; SMN2 | |
| SCHEMBL16871400 | 0.85 | BCHE (0.49) | BCHEMAOBMAOAKMT2ASMN1; SMN2 | |
| SCHEMBL16871401 | 0.85 | BCHE (0.49) | BCHEMAOBMAOAKMT2ASMN1; SMN2 | |
| SCHEMBL16871045 | 0.84 | KMT2A (0.53) | BCHEMAOBMAOAKMT2ASMN1; SMN2 | |
| SCHEMBL16871057 | 0.84 | KMT2A (0.53) | BCHEMAOBMAOAKMT2ASMN1; SMN2 | |
| SCHEMBL16871206 | 0.84 | KMT2A (0.49) | BCHEMAOBMAOAKMT2ASMN1; SMN2 | |
| SCHEMBL16871393 | 0.84 | KMT2A (0.49) | BCHEMAOBMAOAKMT2ASMN1; SMN2 | |
| SCHEMBL16871205 | 0.83 | KMT2A (0.55) | BCHEMAOBMAOAKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130150622-A1 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130150622-A1 | STEREOSELECTIVE SYNTHESIS OF TAPENTADOL AND ITS SALTS | SLC6A2, SLC6A4, SLC6A6 | BCHE 189/4885MAOB 1938/4885MAOA 1824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.