Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.32 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 5/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | MME | P08473 | 6/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 2/20 | 0.30 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5788201 | 0.78 | GAA (0.32) | SIRT2SIRT1SIRT3BACE1 | |
| SCHEMBL9474731 | 0.74 | HSD17B10 (0.39) | SIRT2SIRT1SIRT3BACE1HDAC3 | |
| SCHEMBL1980083 | 0.74 | LMNA (0.37) | — | |
| SCHEMBL6446496 | 0.73 | HDAC3 (0.36) | SIRT2SIRT1SIRT3BACE1HDAC3 | |
| SCHEMBL17995 | 0.71 | HDAC3 (0.36) | SIRT2SIRT1SIRT3HDAC3HDAC1 | |
| SCHEMBL7621151 | 0.70 | HDAC3 (0.37) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL131844 | 0.70 | HDAC3 (0.37) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL11009780 | 0.70 | HDAC3 (0.37) | SIRT2SIRT1SIRT3BACE1HDAC3 | |
| SCHEMBL3066907 | 0.70 | LMNA (0.48) | — | |
| SCHEMBL6501628 | 0.69 | MME (0.44) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120056341-A1 | SILICA NANOCAPSULES FROM NANO-EMULSIONS OBTAINED BY PHASE INVERSION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2012-03-08 | — | — | US | disclosed |
| WO-2010103514-A1 | SILICA NANOCAPSULES FROM NANO-EMULSIONS OBTAINED BY PHASE INVERSION | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD. (IL) | 2010-09-16 | — | — | WO | disclosed |