SCHEMBL1502452

SCHEMBL1502452

CC(C)(CCl)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.58
MAPK1 P28482 1/20 0.44
TSHR P16473 2/20 0.43
CYP2C19 P33261 1/20 0.41
HIF1A Q16665 1/20 0.41
ALDH1A1 P00352 3/20 0.41
ALOX15 P16050 1/20 0.41
KCNN4 O15554 4/20 0.39
ESR1 P03372 2/20 0.39
ESR2 Q92731 2/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5085357 0.97 TAAR1 (0.56) TAAR1MAPK1TSHRCYP2C19HIF1A
SCHEMBL7165155 0.86 SHBG (0.42) TAAR1TSHRESR1ESR2CYP3A4
SCHEMBL11742223 0.80 TAAR1 (0.54) TAAR1MAPK1TSHRCYP2C19HIF1A
SCHEMBL10524759 0.79 TSHR (0.48) MAPK1TSHRALDH1A1MAPT
SCHEMBL3368788 0.78 TAAR1 (0.64) TAAR1MAPK1TSHRCYP2C19HIF1A
SCHEMBL272389 0.77 TAAR1 (0.56) TAAR1MAPK1TSHRCYP2C19HIF1A
SCHEMBL9211954 0.77 TSHR (0.52) TAAR1TSHRCYP2C19ALDH1A1ALOX15
SCHEMBL6015470 0.77 TSHR (0.48) TAAR1MAPK1TSHRCYP2C19HIF1A
SCHEMBL10837089 0.77 MEN1 (0.52) MAPK1TSHRHIF1AKMT2A
Tert-Amylbenzene SCHEMBL131593 0.76 TAAR1 (0.61) TAAR1MAPK1CYP2C19HIF1AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 166 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100344027-C Lithium secondary battery and nonaqueous electrolyte UBE INDUSTRIES (JP) 2007-10-17 CN claimed
CN-1329365-C Indanes and indanones and their use in perfumery GIVAUDAN SA (CH) 2007-08-01 CN claimed
CN-1615294-A Indanes and indanones and their use in perfumery GIVAUDAN SA (CH) 2005-05-11 CN claimed
EP-0192845-B1 PROCESS FOR THE PREPARATION OF PURE METHALLYL BENZENE OR OF BUTENYL BENZENE, AND ITS P-ALKYL DERIVATIVES HÜLS AKTIENGESELLSCHAFT (DE) 1989-02-15 EP claimed
US-4642405-A POLYMERIZATION INHIBITORS HUELS AKTIENGESELLSCHAFT (DE) 1987-02-10 US claimed
EP-0192845-A1 Process for the preparation of pure methallyl benzene or of butenyl benzene, and its p-alkyl derivatives HÜLS AKTIENGESELLSCHAFT (DE) 1986-09-03 EP claimed
JP-55035053-A None JP disclosed
JP-4054133-A None JP disclosed
WO-2024204738-A1 METHOD FOR PRODUCING 1,1-DIMETHYL-1,2-DIHYDRONAPHTHALENE 持田製薬株式会社 2024-10-03 WO disclosed
EP-4426679-A1 SPIRO-(INDANE-FLUORENE) TYPE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2024-09-11 EP disclosed
CN-118251380-A Spiro- (indan-fluorene) compounds and their use in organic electronic devices 多蒂肯独家合成控股公司 2024-06-25 CN disclosed
WO-2023078824-A1 SPIRO-(INDANE-FLUORENE) TYPE COMPOUNDS AND THEIR USE IN ORGANIC ELECTRONICS DOTTIKON ES HOLDING AG (CH) 2023-05-11 WO disclosed
CN-115745457-A High-adaptability concrete superplasticizer, preparation method and application thereof 南京博特新材料有限公司 2023-03-07 CN disclosed
EP-0005541-A2 Substituted piperidine, morpholine or piperidone derivatives, fungicides containing these compounds, process for their preparation and their use, and the use of these compounds as fungicides F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1979-11-28 EP disclosed
US-4058545-A FROM A MAGNESIUM HALIDE AND TETRAORGANO-TIN M&T CHEMICALS INC. (US) 1977-11-15 US disclosed
US-4017525-A Tetra(neophyl) zirconium E. I. DUPONT DE NEMOURS AND COMPANY (US) 1977-04-12 US disclosed
US-4011383-A TETRA(NEOPHYL) ZIRCONIUM AND ITS USE IN PROCESS FOR THE POLYMERIZATION OF OLEFINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-03-08 US disclosed
US-3971767-A Olefin polymerization catalyst system and process for polymerization of olefins E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-07-27 US disclosed
US-3950269-A OLEFIN POLYMERIZATION CATALYST SYSTEM AND PROCESS FOR POLYMERIZATION OF OLEFINS E. I. DU PONT DE NEMOURS & CO. (US) 1976-04-13 US disclosed
US-3932307-A Tetra(neophyl) zirconium and its use in process for the polymerization of olefins E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-01-13 US disclosed