Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1502452 | 0.97 | TAAR1 (0.58) | TAAR1MAPK1TSHRCYP2C19HIF1A | |
| SCHEMBL7165155 | 0.84 | SHBG (0.42) | TAAR1TSHRESR1ESR2CYP3A4 | |
| SCHEMBL11742223 | 0.78 | TAAR1 (0.54) | TAAR1MAPK1TSHRCYP2C19HIF1A | |
| SCHEMBL28272853 | 0.77 | TAAR1 (0.46) | TAAR1MAPK1TSHRCYP2C19HIF1A | |
| SCHEMBL10524759 | 0.77 | TSHR (0.48) | MAPK1TSHRALDH1A1MAPT | |
| SCHEMBL3368788 | 0.76 | TAAR1 (0.64) | TAAR1MAPK1TSHRCYP2C19HIF1A | |
| SCHEMBL10837089 | 0.75 | MEN1 (0.52) | MAPK1TSHRHIF1AKMT2A | |
| SCHEMBL9211954 | 0.75 | TSHR (0.52) | TAAR1TSHRCYP2C19ALDH1A1ALOX15 | |
| SCHEMBL272389 | 0.75 | TAAR1 (0.56) | TAAR1MAPK1TSHRCYP2C19HIF1A | |
| SCHEMBL6015470 | 0.75 | TSHR (0.48) | TAAR1MAPK1TSHRCYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251380-A | Spiro- (indan-fluorene) compounds and their use in organic electronic devices | 多蒂肯独家合成控股公司 | 2024-06-25 | — | — | CN | disclosed |
| US-10577460-B2 | Method for producing polyester | NIPPON SODA CO., LTD. (JP) | 2020-03-03 | — | — | US | disclosed |
| US-20180022867-A1 | METHOD FOR PRODUCING POLYESTER | NIPPON SODA CO., LTD. (JP) | 2018-01-25 | — | — | US | disclosed |
| EP-3248998-A1 | METHOD FOR PRODUCING POLYESTER | Nippon Soda Co., Ltd. (JP) | 2017-11-29 | — | — | EP | disclosed |
| EP-1487886-B1 | SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-08-06 | — | — | EP | disclosed |
| US-7262183-B2 | Substituted 5-membered n-heterocyclic compounds and their uses for treating or preventing neurodegenerative diseases | Instititute of Pharmacology and Toxicology (CN) | 2007-08-28 | — | — | US | disclosed |
| US-7098356-B2 | Substituted indenyl metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-08-29 | — | — | US | disclosed |
| US-20050171166-A1 | Substituted 5-membered n-heterocyclic compounds and their uses for treating or preventing neurodegenerative diseases | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICNI SCIENCES P.L.A. CHINA (CN) | 2005-08-04 | — | — | US | disclosed |
| US-20050143536-A1 | Substituted indenyl metal complexes and polymerization process | DOW GLOBAL TECHNOLOGIES LLC | 2005-06-30 | — | — | US | disclosed |
| EP-1487886-A1 | SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | Dow Global Technologies Inc. (US) | 2004-12-22 | — | — | EP | disclosed |
| WO-2003078483-A1 | SUBSTITUTED INDENYL METAL COMPLEXES AND POLYMERIZATION PROCESS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-09-25 | — | — | WO | disclosed |
| US-6518375-B1 | Trivalent alkyl chromium compound catalyst for the production of an ethylene polymer | JAPAN POLYOLEFINS CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1041085-B1 | Catalyst for the production of ethylene polymer and process for producing ethylene polymer | JAPAN POLYOLEFINS CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-1041085-A1 | Catalyst for the production of ethylene polymer and process for producing ethylene polymer | Japan Polyolefins Co., Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143536-A1 | Substituted indenyl metal complexes and polymerization process | ORC3, SOD1, YAP1 | TAAR1 4168/4885MAPK1 2615/4885TSHR 4707/4885 |
| US-20050171166-A1 | Substituted 5-membered n-heterocyclic compounds and their uses for treating or preventing neurodegenerative diseases | BDNF, NGF, NTRK2 | TAAR1 4533/4885MAPK1 3066/4885TSHR 3344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.