Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15007037 | 0.85 | ALDH1A1 (0.54) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL21253178 | 0.85 | CYP1A2 (0.46) | ALDH1A1L3MBTL1RAB9AMEN1KMT2A | |
| SCHEMBL15006816 | 0.77 | SRD5A2 (0.42) | ALDH1A1SRD5A2L3MBTL1LMNAMAPT | |
| SCHEMBL31090730 | 0.76 | ALDH1A1 (0.52) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL6787662 | 0.74 | ALDH1A1 (0.67) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL17828245 | 0.74 | ALDH1A1 (0.67) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL17828242 | 0.74 | ALDH1A1 (0.67) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| Benzophenone SCHEMBL6662205 | 0.73 | ALDH1A1 (0.82) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| Benzophenone SCHEMBL31040259 | 0.73 | ALDH1A1 (0.93) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 | |
| SCHEMBL9066312 | 0.73 | ALDH1A1 (0.93) | ALDH1A1SRD5A2L3MBTL1ATMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9409861-B2 | Mercapto benzophenone compounds, compositions and preparation method thereof | Insight High Technology (Beijing) Co. Ltd. (CN) | 2016-08-09 | — | — | US | disclosed |
| US-9409861-B2 | Mercapto benzophenone compounds, compositions and preparation method thereof | Insight High Technology (Beijing) Co. Ltd. (CN) | 2016-08-09 | — | — | US | disclosed |
| US-20150246878-A1 | MERCAPTO BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHOD THEREOF | Insight High Technology (Beijing) Co. Ltd. (CN) | 2015-09-03 | — | — | US | disclosed |
| US-20150246878-A1 | MERCAPTO BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHOD THEREOF | Insight High Technology (Beijing) Co. Ltd. (CN) | 2015-09-03 | — | — | US | disclosed |
| US-9061979-B2 | Mercapto benzophenone compounds, compositions and preparations method thereof | Insight High Technology (Beijing) Co. Ltd. (CN) | 2015-06-23 | — | — | US | disclosed |
| US-9061979-B2 | Mercapto benzophenone compounds, compositions and preparations method thereof | Insight High Technology (Beijing) Co. Ltd. (CN) | 2015-06-23 | — | — | US | disclosed |
| US-20130150479-A1 | Mercapto Benzophenone Compounds, Compositions and Preparation Method Thereof | Insight High Technology (Beijing) Co. Ltd. (CN) | 2013-06-13 | — | — | US | disclosed |
| US-20130150479-A1 | Mercapto Benzophenone Compounds, Compositions and Preparation Method Thereof | Insight High Technology (Beijing) Co. Ltd. (CN) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246878-A1 | MERCAPTO BENZOPHENONE COMPOUNDS, COMPOSITIONS AND PREPARATION METHOD THEREOF | MIF, TST, BMI1 | ALDH1A1 73/4885SRD5A2 1071/4885L3MBTL1 3322/4885 |
| US-20130150479-A1 | Mercapto Benzophenone Compounds, Compositions and Preparation Method Thereof | MIF, TST, BMI1 | ALDH1A1 73/4885SRD5A2 1071/4885L3MBTL1 3322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.