Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 5/20 | 0.62 |
| ▸ | NPC1 | O15118 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16834317 | 0.89 | L3MBTL1 (0.75) | CYP1A2CYP2C19CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL7641709 | 0.84 | KDM4E (0.69) | CYP1A2CYP2C19CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL10458651 | 0.84 | CYP1A2 (0.63) | CYP1A2CYP2C19CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL12603165 | 0.84 | L3MBTL1 (0.69) | CYP1A2CYP2C19CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL14314645 | 0.82 | L3MBTL1 (0.72) | CYP1A2CYP2C19CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL15667351 | 0.81 | TDP1 (0.66) | CYP1A2CYP2C19CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL11443005 | 0.81 | MAPK1 (0.52) | CYP1A2CYP2C19CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL21558830 | 0.81 | MAPT (0.66) | CYP1A2CYP2C19CYP2D6ALDH1A1SMN1; SMN2 | |
| SCHEMBL11963241 | 0.81 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2LMNAL3MBTL1KDM4E | |
| SCHEMBL28941901 | 0.81 | L3MBTL1 (0.79) | CYP1A2CYP2C19CYP2D6ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170355669-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-12-14 | — | — | US | disclosed |
| US-9682927-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160362362-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-12-15 | — | — | US | disclosed |
| US-9388125-B2 | Compositions, methods, and systems for the synthesis and use of imaging agents | LANTHEUS MEDICAL IMAGING, INC. (US) | 2016-07-12 | — | — | US | disclosed |
| US-20130149244-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-06-13 | — | — | US | disclosed |
| US-20130149244-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362362-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | FABP3, TNNI3, TNNT2 | CYP1A2 2650/4885CYP2C19 3728/4885CYP2D6 3605/4885 |
| US-20130149244-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | FABP3, TNNI3, TNNT2 | CYP1A2 2650/4885CYP2C19 3728/4885CYP2D6 3605/4885 |
| US-20170355669-A1 | COMPOSITIONS, METHODS, AND SYSTEMS FOR THE SYNTHESIS AND USE OF IMAGING AGENTS | FABP3, TNNI3, TNNT2 | CYP1A2 2650/4885CYP2C19 3728/4885CYP2D6 3605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.