⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12252370 | 0.88 | — | — | |
| SCHEMBL15508460 | 0.81 | — | — | |
| SCHEMBL16907235 | 0.81 | — | — | |
| SCHEMBL15026082 | 0.81 | — | — | |
| SCHEMBL12253293 | 0.77 | LMNA (0.30) | — | |
| SCHEMBL17435720 | 0.76 | FKBP1A (0.31) | — | |
| SCHEMBL12252365 | 0.76 | IDO1 (0.33) | — | |
| SCHEMBL13323840 | 0.75 | FKBP1A (0.31) | — | |
| SCHEMBL12253292 | 0.72 | LMNA (0.30) | — | |
| SCHEMBL19456316 | 0.72 | LMNA (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170224637-A1 | INTRANSAL DELIVERY OF CURCUMIN | DePuy Synthes Products, Inc. (US) | 2017-08-10 | — | — | US | disclosed |
| EP-2749552-A1 | Curcumin-resveratrol hybrids | Codman & Shurtleff, Inc. (US) | 2014-07-02 | — | — | EP | disclosed |
| US-20140163116-A1 | METHOD OF TREATING CANCER USING A CURCUMIN DERIVATIVE | DePuy Synthes Products, LLC (US) | 2014-06-12 | — | — | US | disclosed |
| US-20130150628-A1 | PHARMACEUTICAL COMPOSITION COMPRISING A CURCUMIN DERIVATIVE | DIMAURO THOMAS M (US) | 2013-06-13 | — | — | US | disclosed |