SCHEMBL15026323

SCHEMBL15026323

CCCCCN1/C(=C\C=C2/CCC(/C=C/C3=[N+](CCCCS(=O)(=O)O)c4ccccc4C3(C)C)=C2Cl)C(C)(C)c2ccccc21

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.51
FOLR1 P15328 6/20 0.49
HTR1A P08908 1/20 0.48
PRMT1 Q99873 5/20 0.47
CHRM1 P11229 3/20 0.45
CHRM3 P20309 3/20 0.45
MLNR O43193 1/20 0.45
NR1I2 O75469 1/20 0.45
PGR P06401 1/20 0.45
ADRB1 P08588 1/20 0.45
ADORA3 P0DMS8 1/20 0.45
DRD2 P14416 1/20 0.45
ADRA2B P18089 1/20 0.45
ADRA2C P18825 1/20 0.45
CNR1 P21554 1/20 0.45
DRD1 P21728 1/20 0.45
TBXA2R P21731 1/20 0.45
SLC6A2 P23975 1/20 0.45
HRH2 P25021 1/20 0.45
HTR2C P28335 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12364521 1.00 PTPN1 (0.51) PTPN1FOLR1HTR1APRMT1CHRM1
SCHEMBL14666851 1.00 PTPN1 (0.51) PTPN1FOLR1HTR1APRMT1CHRM1
SCHEMBL9101895 0.97 PTPN1 (0.53) PTPN1FOLR1HTR1APRMT1CHRM1
SCHEMBL12891552 0.97 PTPN1 (0.53) PTPN1FOLR1HTR1APRMT1CHRM1
SCHEMBL15026326 0.97 PTPN1 (0.53) PTPN1FOLR1HTR1APRMT1CHRM1
SCHEMBL9101901 0.97 PTPN1 (0.53) PTPN1FOLR1HTR1APRMT1CHRM1
SCHEMBL14364022 0.97 PTPN1 (0.53) PTPN1FOLR1HTR1APRMT1CHRM1
SCHEMBL15026321 0.97 FOLR1 (0.52) PTPN1FOLR1HTR1APRMT1CHRM1
SCHEMBL10033460 0.97 FOLR1 (0.52) PTPN1FOLR1HTR1APRMT1CHRM1
SCHEMBL13528757 0.97 FOLR1 (0.52) PTPN1FOLR1HTR1APRMT1CHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9370589-B2 Switching fluorescent nanoparticle probe and fluorescent particle imaging method using same SHIMADZU CORPORATION (JP) 2016-06-21 US disclosed
US-20130149252-A1 SWITCHING FLUORESCENT NANOPARTICLE PROBE AND FLUORESCENT PARTICLE IMAGING METHOD USING SAME KYOTO UNIVERSITY (JP) 2013-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130149252-A1 SWITCHING FLUORESCENT NANOPARTICLE PROBE AND FLUORESCENT PARTICLE IMAGING METHOD USING SAME TNNI3, TTN, TNNT2 PTPN1 3612/4885FOLR1 1845/4885HTR1A 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.