SCHEMBL150273

SCHEMBL150273

O=c1ccn([C@H]2C[C@H](O)[C@@H](C(Br)OP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
DUT P33316 2/20 0.52
P2RY2 P41231 16/20 0.49
P2RY4 P51582 10/20 0.49
POLA1 P09884 1/20 0.47
P2RY6 Q15077 6/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL986334 0.90 DUT (0.52) DUTP2RY2P2RY4P2RY6
SCHEMBL1129336 0.88 DUT (0.52) DUTP2RY2P2RY4POLA1P2RY6
SCHEMBL7745800 0.88 DUT (0.55) DUTP2RY2P2RY4POLA1P2RY6
SCHEMBL8441083 0.88 DUT (0.52) DUTP2RY2P2RY4POLA1P2RY6
SCHEMBL16670190 0.87 DUT (0.51) DUTP2RY2P2RY4POLA1P2RY6
SCHEMBL8439797 0.87 DUT (0.51) DUTP2RY2P2RY4POLA1P2RY6
SCHEMBL1129230 0.86 DUT (0.54) DUTP2RY2P2RY4POLA1P2RY6
SCHEMBL14855438 0.86 DUT (0.50) DUTP2RY2P2RY4POLA1P2RY6
SCHEMBL8436034 0.86 DUT (0.52) DUTP2RY2P2RY4POLA1P2RY6
SCHEMBL8441386 0.84 DUT (0.51) DUTP2RY2P2RY4POLA1P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 210 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7087375-B1 Method for determining the mechanism of HIV RT inhibitors VIRCO, N.V. (BE) 2006-08-08 US claimed
EP-3921440-B1 METHOD AND PRODUCTS FOR PRODUCING FUNCTIONALISED SINGLE STRANDED OLIGONUCLEOTIDES MOLIGO TECH AB (SE) 2024-03-27 EP disclosed
CN-117377774-A Method for sensitive analyte detection and kit therefor 卡维迪有限公司 2024-01-09 CN disclosed
US-20230079822-A1 METHOD AND PRODUCTS FOR PRODUCING SINGLE STRANDED DNA POLYNUCLEOTIDES MOLIGO TECHNOLOGIES AB (SE) 2023-03-16 US disclosed
EP-4110914-A1 METHOD AND PRODUCTS FOR PRODUCING SINGLE STRANDED DNA POLYNUCLEOTIDES Moligo Technologies AB (SE) 2023-01-04 EP disclosed
CN-109868309-B Single-stranded DNA amplification method based on universal base substitution insertion 苏州恩可医药科技有限公司 2022-11-11 CN disclosed
CN-109852727-B HBV-cccDNA detection method and kit based on universal base substitution insertion 苏州恩可医药科技有限公司 2022-10-11 CN disclosed
EP-1583843-B1 SINGLE PRIMER WHOLE GENOME AMPLIFICATION QIAGEN GMBH (DE) 2018-07-18 EP disclosed
EP-3294326-A1 PRIME-BOOST REGIMENS INVOLVING ADMINISTRATION OF AT LEAST ONE MRNA CONSTRUCT CureVac AG (DE) 2018-03-21 EP disclosed
US-9593366-B2 Individually synthesized primers to be used in whole genome amplification QIAGEN GAITHERSBURG, INC. (US) 2017-03-14 US disclosed
US-5549711-A Prosthetic foot and keel therefor having progressive stiffening under increasing load M+IND (MODEL + INSTRUMENT DEVELOPMENT) (US) 1996-08-27 US disclosed
EP-0720456-A1 PROSTHETIC FOOT AND KEEL THEREFOR HAVING PROGRESSIVE STIFFENING UNDER INCREASING LOAD M+IND (Model + Instrument Development) (US) 1996-07-10 EP disclosed
EP-0686202-A1 PRENATAL SCREENING BRANDEIS UNIVERSITY (US) 1995-12-13 EP disclosed
WO-1995008967-A1 PROSTHETIC FOOT AND KEEL THEREFOR HAVING PROGRESSIVE STIFFENING UNDER INCREASING LOAD M+IND (MODEL + INSTRUMENT DEVELOPMENT) (US) 1995-04-06 WO disclosed
WO-1994018344-A1 PRENATAL SCREENING BRANDEIS UNIVERSITY (US) 1994-08-18 WO disclosed
EP-0417161-A4 SOLID-PHASE SEQUENCING METHOD FOR SINGLE- AND DOUBLE-STRANDED NUCLEIC ACIDS 1992-08-12 EP disclosed
EP-0417161-A1 SOLID-PHASE SEQUENCING METHOD FOR SINGLE- AND DOUBLE-STRANDED NUCLEIC ACIDS APPLIED BIOSYSTEMS, INC. (US) 1991-03-20 EP disclosed
WO-1990001562-A1 SOLID-PHASE SEQUENCING METHOD FOR SINGLE- AND DOUBLE-STRANDED NUCLEIC ACIDS APPLIED BIOSYSTEMS, INC. (US) 1990-02-22 WO disclosed
WO-1985002415-A1 NON RADIOACTIVE PROBE AND PROCESS FOR THE CHARACTERIZATION OF A DTERMINED NUCLEOTIDE SEQUENCE AND MEANS FOR THE PRODUCTION OF SAID NON RADIOACTIVE PROBE INSTITUT PASTEUR (FR) 1985-06-06 WO disclosed
EP-0143059-A1 Non-radioactive probe and process for the characterization of a particular nucleotide sequence, and means for the production of this non-radioactive probe INSTITUT PASTEUR (FR) 1985-05-29 EP disclosed