Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 4/20 | 0.52 |
| ▸ | HRH1 | P35367 | 4/20 | 0.47 |
| ▸ | PLAT | P00750 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028358 | 0.87 | NMT1 (0.56) | NMT1HRH1 | |
| SCHEMBL15028224 | 0.86 | NMT1 (0.57) | NMT1HRH1PLAT | |
| SCHEMBL15028296 | 0.86 | NMT1 (0.55) | NMT1HRH1 | |
| SCHEMBL15028221 | 0.83 | NMT1 (0.54) | NMT1HRH1 | |
| SCHEMBL15014299 | 0.80 | PDE4B (0.46) | — | |
| SCHEMBL3156343 | 0.78 | PRMT5 (0.47) | NMT1HRH1 | |
| SCHEMBL25910681 | 0.78 | DHODH (0.54) | — | |
| SCHEMBL15012535 | 0.78 | NMT1 (0.68) | NMT1HRH1 | |
| SCHEMBL15028361 | 0.77 | HTR6 (0.55) | NMT1HRH1 | |
| SCHEMBL15028295 | 0.77 | NMT1 (0.57) | NMT1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013083991-A1 | NOVEL COMPOUNDS AND THEIR USE IN THERAPY | IMPERIAL INNOVATIONS LIMITED (GB) | 2013-06-13 | — | — | WO | disclosed |