Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 3/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 3/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15028224 | 0.87 | NMT1 (0.57) | NMT1HRH1 | |
| SCHEMBL15012535 | 0.87 | NMT1 (0.68) | NMT1HRH1MMP2MMP9MMP12 | |
| SCHEMBL15028361 | 0.87 | HTR6 (0.55) | NMT1HTR6HRH1MMP2MMP9 | |
| SCHEMBL15028291 | 0.86 | NMT1 (0.52) | NMT1HRH1 | |
| SCHEMBL15028221 | 0.84 | NMT1 (0.54) | NMT1HRH1 | |
| SCHEMBL15028362 | 0.83 | SLC6A2 (0.60) | NMT1HRH1 | |
| SCHEMBL15028295 | 0.83 | NMT1 (0.57) | NMT1HRH1 | |
| SCHEMBL15028198 | 0.81 | NMT1 (0.82) | NMT1 | |
| SCHEMBL8425730 | 0.79 | HTT (0.56) | MMP2MMP9MMP12 | |
| SCHEMBL15012287 | 0.78 | HRH1 (0.53) | NMT1HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013083991-A1 | NOVEL COMPOUNDS AND THEIR USE IN THERAPY | IMPERIAL INNOVATIONS LIMITED (GB) | 2013-06-13 | — | — | WO | disclosed |