Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27139420 | 0.96 | DGKA (0.50) | DGKACYP1A2HTR2CPRSS1PRSS2 | |
| SCHEMBL14365471 | 0.92 | DGKA (0.47) | DGKACYP1A2HTR2CPRSS1PRSS2 | |
| SCHEMBL3764429 | 0.92 | DGKA (0.54) | DGKACYP1A2HTR2CPRSS1PRSS2 | |
| SCHEMBL11853523 | 0.92 | DGKA (0.54) | DGKACYP1A2HTR2CPRSS1PRSS2 | |
| SCHEMBL11847129 | 0.92 | DGKA (0.54) | DGKACYP1A2HTR2CPRSS1PRSS2 | |
| SCHEMBL27588223 | 0.92 | DGKA (0.54) | DGKACYP1A2HTR2CPRSS1PRSS2 | |
| Hydrochloric Acid SCHEMBL11847579 | 0.90 | DGKA (0.52) | DGKACYP1A2HTR2CPRSS1PRSS2 | |
| Sulfuric Acid SCHEMBL23572703 | 0.89 | DGKA (0.44) | DGKACYP1A2HTR2CPRSS1PRSS2 | |
| SCHEMBL28577945 | 0.88 | CYP1A2 (0.59) | DGKACYP1A2HTR2CPRSS1PRSS2 | |
| SCHEMBL11859829 | 0.88 | CYP1A2 (0.54) | DGKACYP1A2HTR2CPRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130148077-A1 | CONTACT LENSES WITH ENZYMATICALLY DEGRADABLE COATINGS THEREON | NOVARTIS AG (CH) | 2013-06-13 | — | — | US | disclosed |