Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | PLG | P00747 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11847129 | 1.00 | DGKA (0.54) | DGKACYP1A2HTR2CALDH1A1THRB | |
| SCHEMBL11853523 | 1.00 | DGKA (0.54) | DGKACYP1A2HTR2CALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL11847579 | 0.98 | DGKA (0.52) | DGKACYP1A2HTR2CALDH1A1THRB | |
| SCHEMBL11859829 | 0.95 | CYP1A2 (0.54) | DGKACYP1A2HTR2CALDH1A1THRB | |
| SCHEMBL13088732 | 0.94 | PRSS1 (0.50) | DGKACYP1A2HTR2CALDH1A1THRB | |
| SCHEMBL23572763 | 0.93 | DGKA (0.61) | DGKACYP1A2HTR2CALDH1A1THRB | |
| SCHEMBL20824974 | 0.93 | CYP1A2 (0.61) | DGKACYP1A2HTR2CALDH1A1THRB | |
| SCHEMBL15028624 | 0.92 | DGKA (0.47) | DGKACYP1A2HTR2CALDH1A1THRB | |
| SCHEMBL13258632 | 0.92 | LMNA (0.65) | DGKACYP1A2HTR2CALDH1A1THRB | |
| SCHEMBL14365471 | 0.92 | DGKA (0.47) | DGKACYP1A2HTR2CALDH1A1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8455413-B2 | Additive for oils and lubricant comprising the same | KH NEOCHEM CO., LTD. (JP) | 2013-06-04 | — | — | US | disclosed |
| US-20100298183-A1 | ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME | KYOWA HAKKO CHEMICAL CO., LTD. (JP) | 2010-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100298183-A1 | ADDITIVE FOR OILS AND LUBRICANT COMPRISING THE SAME | NCOA2, NCOR2, NR1H2 | DGKA 3161/4885CYP1A2 162/4885HTR2C 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.