Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28918349 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL28934761 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL28934976 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL8639683 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL3900347 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL5950112 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL28935026 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL5950521 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL2962251 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL153697 | 0.98 | LIPG (0.51) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118844448-A | Preparation method of long-acting antibacterial liquid | 孙国明 | 2024-10-29 | — | — | CN | claimed |
| CN-118703064-A | Intercalation modification process of montmorillonite and its product | 苏州和塑美科技有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118459895-A | Preparation method of high-whiteness organic montmorillonite modified polyolefin composite material and product thereof | 苏州和塑美科技有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-116425699-A | Compound for purifying 2-chloro-5-chloromethylthiazole, preparation method and application | 湖南璟丰化工科技有限公司 | 2023-07-14 | — | — | CN | claimed |
| CN-116394618-A | Antibacterial high-transparency low-fog BOPET film | 江苏裕兴薄膜科技股份有限公司 | 2023-07-07 | — | — | CN | claimed |
| CN-116349679-A | Composite disinfection and sterilization method | 孙国明 | 2023-06-30 | — | — | CN | claimed |
| CN-116023048-A | Cement clinker and method for preparing cement by using same | 湖南创速新材料有限公司 | 2023-04-28 | — | — | CN | claimed |
| CN-115792090-A | Method for measuring content of fatty acid soap in fatty acyl amino acid salt product | 江南大学 | 2023-03-14 | — | — | CN | claimed |
| CN-115433376-A | Preparation method of long-acting disinfection and sterilization fabric or fiber | 孙国明 | 2022-12-06 | — | — | CN | claimed |
| CN-112022725-B | Application of metal citrate in root canal treatment and preparation prepared from metal citrate | 昆明蓝橙口腔医院有限责任公司 | 2022-09-20 | — | — | CN | claimed |
| CN-114644876-A | Photocuring coating composition, photocuring coating and application | 常州强力电子新材料股份有限公司 | 2022-06-21 | — | — | CN | claimed |
| CN-114600900-A | Organosilicon quaternary ammonium salt composite antibacterial agent and preparation method thereof | 天津工业大学 | 2022-06-10 | — | — | CN | claimed |
| WO-2022052631-A1 | APPLICATION OF CITRATE METAL SALT IN ENDODONTIC TREATMENT, AND FORMULATION OBTAINED BY PREPARATION | 昆明蓝橙口腔医院有限责任公司 | 2022-03-17 | — | — | WO | claimed |
| WO-2017112721-A1 | CORROSION INHIBITORS AND RELATED PROCESSES FOR THEIR PRODUCTION AND USE | ALBEMARLE CORPORATION (US) | 2017-06-29 | — | — | WO | claimed |
| EP-0346655-B1 | AN IMPROVED METHOD FOR PREPARING POLYMER SURFACES FOR SUBSEQUENT PLATING THEREON, AND IMPROVED METAL-PLATED PLASTIC ARTICLES MADE THEREFROM | GENERAL ELECTRIC COMPANY (US) | 1993-08-18 | — | — | EP | claimed |
| EP-0346655-A1 | An improved method for preparing polymer surfaces for subsequent plating thereon, and improved metal-plated plastic articles made therefrom | GENERAL ELECTRIC COMPANY (US) | 1989-12-20 | — | — | EP | claimed |
| US-4873136-A | MILD ETCHING; REMOVAL OF RESIDUAL FILM WITH CATIONIC SURFACTANT | GENERAL ELECTRIC COMPANY (US) | 1989-10-10 | — | — | US | claimed |
| JP-57156417-A | — | — | None | — | — | JP | disclosed |
| US-4140762-A | HEMAGGLUTININ AND NEURAMINIDASE COMPONENTS OF VIRUS | SANDOZ LTD. (CH) | 1979-02-20 | — | — | US | disclosed |
| US-4064232-A | Process for isolating the immunogenic components of influenza viruses | SANDOZ LTD. (CH) | 1977-12-20 | — | — | US | disclosed |