Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.50 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 4/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.41 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | EP300 | Q09472 | 1/20 | 0.40 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.40 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.40 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.40 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28918349 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL28934761 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL28934976 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL8639683 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL5950112 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL28935026 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL5950521 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL1502929 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| Bromide SCHEMBL2962251 | 1.00 | LIPG (0.50) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 | |
| SCHEMBL153697 | 0.98 | LIPG (0.51) | LIPGNR1H2NR1H3CYSLTR2CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120157854-A | Preparation method for synthesizing ADHC-based homopolyester based on dihydroxyaromatic acid carbonate | 沈阳工业大学 | 2025-06-17 | — | — | CN | claimed |
| CN-114929340-B | Methods and agents for glaucoma | 奥夫博医疗创新有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-120036314-A | Preparation method of quaternary ammonium salt type composite algicide | 上海大学 | 2025-05-27 | — | — | CN | claimed |
| CN-119898789-A | Flower-like sphere mordenite as well as preparation method and application thereof | 中国石油化工股份有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-119837935-A | Pericarpium citri reticulatae extract with hair loss prevention and hair growth effects, and preparation method and application thereof | 广东邑祥陈皮有限公司 | 2025-04-18 | — | — | CN | claimed |
| CN-119793215-A | Defect-free nanofiltration membrane containing TaPa-COF interlayer | 南京工业大学 | 2025-04-11 | — | — | CN | claimed |
| CN-119775979-A | Stable foam control agent with rapid dispersion | 江苏四新科技应用研究所股份有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-119659198-A | Surface active alcohol-free fountain functional water and preparation method thereof | 中山市富日印刷材料有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-119674026-A | Silicon-carbon composite material, preparation method thereof, pole piece and battery | 宁波杉杉新材料科技有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-119674023-A | Tin-carbon composite material, preparation method thereof, pole piece and electrochemical device | 宁波杉杉新材料科技有限公司 | 2025-03-21 | — | — | CN | claimed |
| CN-111165478-A | Foam type sterilization, disinfection and air purification agent and preparation method and application thereof | 南通大学 | 2020-05-19 | — | — | CN | claimed |
| CN-110973137-A | Efficient environment-friendly disinfection composition and preparation method thereof | 山西海博贝马生物科技有限公司 | 2020-04-10 | — | — | CN | claimed |
| CN-110746652-A | Preparation method of polyolefin VOC (volatile organic compound) improved filler and polyolefin composite material | 安徽江淮汽车集团股份有限公司 | 2020-02-04 | — | — | CN | claimed |
| CN-107057799-B | Functionalized graphene powder, lubricating oil containing functionalized graphene powder, and preparation method and application of functionalized graphene powder | 中国科学院过程工程研究所 | 2020-01-31 | — | — | CN | claimed |
| CN-110583649-A | Deodorant composition with antibacterial function and preparation method thereof | 苏州市易柯露环保科技有限公司 | 2019-12-20 | — | — | CN | claimed |
| CN-110591055-A | Cardol epoxy resin and preparation method thereof | 浙江万盛股份有限公司 | 2019-12-20 | — | — | CN | claimed |
| EP-1160213-B1 | New frosting method for glass comprising a rinsing step with a salt solution and resulting frosted objects | SEPPIC SA (FR) | 2009-03-04 | — | — | EP | claimed |
| US-20060140888-A1 | Whitening agent containing crystalline molecular complex of hydroquinone and surfactant | CIRCLE FOR THE PROMOTION OF SCIENCE AND ENGINEERING, THE (JP) | 2006-06-29 | — | — | US | claimed |
| US-6471880-B1 | Process for chemical roughening of glass comprising rinsing with salt solution and article obtained thereby | SOCIETE D'EXPLOITATION DE PRODUITS POUR LES INDUSTRIES CHIMIQUES SEPPIC (FR) | 2002-10-29 | — | — | US | claimed |
| US-4299775-A | Process for the preparation of 3-cyano-3,5,5-trimethylcyclohexanone | PCUK PRODUITS CHIMIQUES UGINE KUHLMANN (FR) | 1981-11-10 | — | — | US | claimed |