SCHEMBL15030675

SCHEMBL15030675

C1=CC(c2cccc(-n3c4ccccc4c4ccccc43)c2)CC(n2c3ccccc3c3ccccc32)=C1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
HDAC4 P56524 1/20 0.31
FOLH1 Q04609 1/20 0.30
KDR P35968 1/20 0.30
SIGMAR1 Q99720 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5028223 0.90 KDM4E (0.36) KDM4EATML3MBTL1HDAC4
SCHEMBL27333558 0.85 KDM4E (0.36) KDM4EATML3MBTL1HDAC4
SCHEMBL21300839 0.85 KDM4E (0.36) KDM4EATML3MBTL1HDAC4
SCHEMBL20258147 0.82 KDM4E (0.35) KDM4EATML3MBTL1
SCHEMBL25930509 0.81 KDM4E (0.40) KDM4EATML3MBTL1HDAC4KDR
SCHEMBL20077874 0.80 HDAC4 (0.41) KDM4EATML3MBTL1HDAC4
SCHEMBL21182171 0.80 KDM4E (0.36) KDM4EATML3MBTL1
SCHEMBL19721366 0.80 KDM4E (0.42) KDM4EATML3MBTL1HDAC4
SCHEMBL26178246 0.79 L3MBTL1 (0.41) KDM4EATML3MBTL1HDAC4KDR
SCHEMBL26456567 0.79 HDAC4 (0.41) KDM4EATML3MBTL1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3112439-A1 LUMINESCENT MATERIAL, ORGANIC LUMINESCENT ELEMENT, AND COMPOUND Kyulux, Inc. (JP) 2017-01-04 EP disclosed
WO-2013083216-A1 SPIRO DIHYDROACRIDINE DERIVATIVES AND THE USE THEREOF AS MATERIALS FOR ORGANIC ELECTROLUMINESCENCE DEVICES MERCK PATENT GMBH (DE) 2013-06-13 WO disclosed