SCHEMBL26456567

SCHEMBL26456567

C1=CC(c2ccccc2)CC(n2c3ccccc3c3cc(-c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5ccc(-c6ccccc6)cc5)cc4)ccc32)=C1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.41
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
TSPO P30536 1/20 0.34
PTGER4 P35408 2/20 0.33
EDNRB P24530 1/20 0.30
EDNRA P25101 1/20 0.30
DNM1 Q05193 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20077874 0.99 HDAC4 (0.41) HDAC4KDM4EATML3MBTL1TSPO
SCHEMBL26178246 0.95 L3MBTL1 (0.41) HDAC4KDM4EATML3MBTL1TSPO
SCHEMBL21300839 0.93 KDM4E (0.36) HDAC4KDM4EATML3MBTL1TSPO
SCHEMBL19452632 0.93 HDAC4 (0.35) HDAC4KDM4EATML3MBTL1TSPO
SCHEMBL5028223 0.91 KDM4E (0.36) HDAC4KDM4EATML3MBTL1TSPO
SCHEMBL25117363 0.87
SCHEMBL27333558 0.87 KDM4E (0.36) HDAC4KDM4EATML3MBTL1
SCHEMBL26283393 0.86 PTGER4 (0.31) HDAC4PTGER4
SCHEMBL23228071 0.85 TSPO (0.31) HDAC4TSPO
SCHEMBL24231801 0.85 KDM4E (0.35) HDAC4KDM4EATML3MBTL1TSPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230139045-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE SAMSUNG SDI CO., LTD. (KR) 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230139045-A1 COMPOUND FOR ORGANIC OPTOELECTRONIC DEVICE, COMPOSITION FOR ORGANIC OPTOELECTRONIC DEVICE, ORGANIC OPTOELECTRONIC DEVICE AND DISPLAY DEVICE OXER1, OCIAD1, OR10J3 HDAC4 4344/4885KDM4E 3961/4885ATM 3712/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.