Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247367 | 0.83 | — | — | |
| SCHEMBL2398492 | 0.83 | — | — | |
| SCHEMBL27674852 | 0.81 | LMNA (0.48) | ALDH1A1LMNATSHR | |
| SCHEMBL28323853 | 0.79 | LMNA (0.52) | ALDH1A1LMNATSHR | |
| SCHEMBL8583831 | 0.79 | LMNA (0.52) | ALDH1A1LMNATSHR | |
| SCHEMBL4591910 | 0.79 | LMNA (0.52) | ALDH1A1LMNATSHR | |
| SCHEMBL17194868 | 0.75 | ALDH1A1 (0.56) | ALDH1A1LMNATSHR | |
| SCHEMBL20045116 | 0.75 | ALDH1A1 (0.56) | ALDH1A1LMNATSHR | |
| SCHEMBL14700022 | 0.75 | LMNA (0.64) | ALDH1A1LMNATSHR | |
| SCHEMBL17195054 | 0.75 | ALDH1A1 (0.56) | ALDH1A1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465672-B2 | Tetrahydropyran compounds | MERCK PATENT GMBH (DE) | 2013-06-18 | — | — | US | disclosed |