Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15031312 | 0.85 | PKM (0.47) | PKMGAAKMT2AACSS2MEN1 | |
| SCHEMBL13211820 | 0.81 | NPC1 (0.61) | PKMCCR2GAAKMT2AACSS2 | |
| SCHEMBL11245499 | 0.79 | PKM (0.54) | PKMGAAACSS2 | |
| SCHEMBL21169293 | 0.79 | DRD3 (0.61) | DRD3GAAKMT2AMEN1POLB | |
| SCHEMBL4356333 | 0.79 | PKM (0.58) | PKMCCR2GAAACSS2 | |
| SCHEMBL28956652 | 0.74 | PTPN1 (0.64) | KMT2AMEN1KDM4ERXFP1RAB9A | |
| SCHEMBL123085 | 0.74 | PTPN1 (0.64) | KMT2AMEN1KDM4ERXFP1RAB9A | |
| SCHEMBL10282567 | 0.72 | DRD4 (0.67) | CCR2KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL21652000 | 0.71 | CARM1 (0.64) | DRD3PKMGAAKMT2AMEN1 | |
| SCHEMBL10123862 | 0.70 | TSHR (0.58) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465921-B2 | Hybridization and mismatch discrimination using oligonucleotides conjugated to minor groove binders | ELITECH HOLDING B.V. (NL) | 2013-06-18 | — | — | US | disclosed |