Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 10/20 | 0.58 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6893243 | 0.88 | GRM2 (0.60) | GRM2ALKIGF1R | |
| Hydrochloric Acid SCHEMBL1502962 | 0.88 | GRM2 (0.59) | GRM2ALKIGF1R | |
| SCHEMBL6890122 | 0.86 | GRM2 (0.69) | GRM2 | |
| SCHEMBL6893000 | 0.84 | GRM2 (0.56) | GRM2 | |
| SCHEMBL6891956 | 0.82 | GRM2 (0.58) | GRM2 | |
| SCHEMBL6891800 | 0.80 | GRM2 (0.63) | GRM2ALDH1A1TP53 | |
| SCHEMBL6893676 | 0.80 | GRM2 (0.67) | GRM2 | |
| SCHEMBL6893180 | 0.78 | GRM2 (0.59) | GRM2 | |
| SCHEMBL1503021 | 0.77 | GRM2 (0.63) | GRM2 | |
| SCHEMBL1503074 | 0.77 | GRM2 (0.63) | GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034741-A1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2011-03-24 | — | — | WO | claimed |
| WO-2011034741-A1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2011-03-24 | — | — | WO | disclosed |