Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | AR | P10275 | 7/20 | 0.54 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17658051 | 0.91 | BLM (0.63) | BLMARTAS2R14 | |
| SCHEMBL14289402 | 0.85 | AR (0.59) | ARCYP2C19 | |
| SCHEMBL31125146 | 0.84 | AR (0.65) | BLMARCYP2C19 | |
| SCHEMBL14916193 | 0.84 | AR (0.55) | BLMAR | |
| SCHEMBL5247689 | 0.84 | TAS2R14 (0.60) | BLMARTAS2R14 | |
| SCHEMBL31125175 | 0.83 | KDR (0.76) | BLMARCYP2C19 | |
| SCHEMBL5664793 | 0.83 | AR (0.55) | ARTAS2R14 | |
| SCHEMBL9430893 | 0.83 | AR (0.63) | ARCYP2C19 | |
| SCHEMBL324379 | 0.82 | AR (0.56) | BLMARTAS2R14CYP2C19 | |
| SCHEMBL2980069 | 0.82 | AR (0.59) | ARCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013084138-A1 | CYCLIC UREA DERIVATIVES AS ANDROGEN RECEPTOR ANTAGONISTS | NOVARTIS AG (CH) | 2013-06-13 | — | — | WO | disclosed |