Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 8/20 | 0.56 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17658051 | 0.88 | BLM (0.63) | ARTAS2R14BLMSLC22A12 | |
| SCHEMBL5247689 | 0.86 | TAS2R14 (0.60) | ARTAS2R14BLMSLC22A12 | |
| SCHEMBL14289402 | 0.85 | AR (0.59) | ARCYP2C19 | |
| SCHEMBL2980069 | 0.85 | AR (0.59) | ARCYP2C19 | |
| SCHEMBL18187538 | 0.85 | AR (0.59) | ARTAS2R14BLMSLC22A12 | |
| SCHEMBL19529658 | 0.84 | AR (0.52) | ARTAS2R14SLC22A12 | |
| SCHEMBL21924973 | 0.84 | TGM2 (0.54) | ARTAS2R14BLM | |
| SCHEMBL29415541 | 0.83 | AR (0.52) | ARTAS2R14CYP2C19 | |
| SCHEMBL202386 | 0.83 | AR (0.52) | ARTAS2R14CYP2C19 | |
| SCHEMBL202266 | 0.83 | AR (0.52) | ARTAS2R14BLMCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590953-A1 | TETRAZOLE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | Convergence Pharmaceuticals Limited (GB) | 2013-05-15 | — | — | EP | disclosed |
| WO-2012004604-A1 | TETRAZOLE COMPOUNDS AS CALCIUM CHANNEL BLOCKERS | Convergence Pharmaceuticals Limited (GB) | 2012-01-12 | — | — | WO | disclosed |