SCHEMBL15033263

SCHEMBL15033263

CC(C)=CCCC(C)C1CCC2C3CCC4C(C)(C)C(C(=O)Oc5cc(N)cc(N)c5)CCC4(C)C3CCC12C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.46
GPBAR1 Q8TDU6 5/20 0.41
HSD17B10 Q99714 3/20 0.41
TDP1 Q9NUW8 3/20 0.41
AKR1B10 O60218 2/20 0.41
AKR1B1 P15121 2/20 0.41
EPHA2 P29317 2/20 0.41
LMNA P02545 2/20 0.41
EFNA1 P20827 1/20 0.41
PSEN1 P49768 1/20 0.41
PSEN2 P49810 1/20 0.41
APH1B Q8WW43 1/20 0.41
NCSTN Q92542 1/20 0.41
APH1A Q96BI3 1/20 0.41
PSENEN Q9NZ42 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
HIF1A Q16665 3/20 0.39
VDR P11473 3/20 0.39
CYP2C9 P11712 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL105231 0.85 RORC (0.49) RORCGPBAR1HSD17B10TDP1AKR1B10
SCHEMBL105225 0.83 RORC (0.47) RORCGPBAR1HSD17B10TDP1AKR1B10
SCHEMBL15935558 0.82 RORC (0.46) RORCGPBAR1HSD17B10TDP1AKR1B10
SCHEMBL10015978 0.82 RORC (0.46) RORCGPBAR1HSD17B10TDP1AKR1B10
SCHEMBL10054759 0.81 RORC (0.47) RORCGPBAR1HSD17B10TDP1AKR1B10
SCHEMBL12172527 0.80 RORC (0.41) RORCGPBAR1HSD17B10TDP1AKR1B10
SCHEMBL17430693 0.78 RORC (0.42) RORCLMNAUSP2PTPN1CYP2C19
SCHEMBL19197390 0.77 USP2 (0.52) RORCGPBAR1HSD17B10TDP1AKR1B10
SCHEMBL23395804 0.77 RORC (0.47) RORCGPBAR1HSD17B10TDP1AKR1B10
SCHEMBL10015980 0.77 RORC (0.47) RORCGPBAR1HSD17B10TDP1AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130162920-A1 LIQUID CRYSTAL DISPLAY PANEL, LIQUID CRYSTAL DISPLAY DEVICE, AND POLYMER FOR ALIGNMENT FILM MATERIAL SHARP KABUSHIKI KAISHA (JP) 2013-06-27 US disclosed
US-20130162920-A1 LIQUID CRYSTAL DISPLAY PANEL, LIQUID CRYSTAL DISPLAY DEVICE, AND POLYMER FOR ALIGNMENT FILM MATERIAL SHARP KABUSHIKI KAISHA (JP) 2013-06-27 US disclosed
US-20130155362-A1 LIQUID CRYSTAL DISPLAY PANEL, LIQUID CRYSTAL DISPLAY DEVICE, AND POLYMER FOR ALIGNMENT FILM MATERIAL SHARP KABUSHIKI KAISHA (JP) 2013-06-20 US disclosed
US-20130155362-A1 LIQUID CRYSTAL DISPLAY PANEL, LIQUID CRYSTAL DISPLAY DEVICE, AND POLYMER FOR ALIGNMENT FILM MATERIAL SHARP KABUSHIKI KAISHA (JP) 2013-06-20 US disclosed