Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HTT | P42858 | 2/20 | 0.69 |
| ▸ | TGM2 | P21980 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | IDO1 | P14902 | 1/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.69 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.56 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.56 |
| ▸ | CDK1 | P06493 | 1/20 | 0.56 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.56 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28985650 | 1.00 | ALDH1A1 (0.69) | ALDH1A1MAPTSMN1; SMN2HTTTGM2 | |
| SCHEMBL14524539 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2HTTTGM2 | |
| SCHEMBL249817 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2HTTTGM2 | |
| SCHEMBL249816 | 0.84 | ALDH1A1 (0.64) | ALDH1A1MAPTSMN1; SMN2HTTTGM2 | |
| SCHEMBL15991939 | 0.82 | MAPT (0.57) | ALDH1A1MAPTSMN1; SMN2HTTTGM2 | |
| SCHEMBL14653700 | 0.82 | MAPT (0.57) | ALDH1A1MAPTSMN1; SMN2HTTTGM2 | |
| SCHEMBL9926479 | 0.82 | TGM2 (1.00) | ALDH1A1MAPTSMN1; SMN2HTTTGM2 | |
| SCHEMBL30005115 | 0.82 | TGM2 (1.00) | ALDH1A1MAPTSMN1; SMN2HTTTGM2 | |
| SCHEMBL3245039 | 0.80 | MAPT (0.77) | ALDH1A1MAPTSMN1; SMN2HTTTGM2 | |
| SCHEMBL30952119 | 0.80 | MAPT (0.77) | ALDH1A1MAPTSMN1; SMN2HTTTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130156795-A1 | METHODS FOR INHIBITION OF CELL PROLIFERATION, SYNERGISTIC TRANSCRIPTION MODULES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-06-20 | — | — | US | disclosed |
| US-20130156795-A1 | METHODS FOR INHIBITION OF CELL PROLIFERATION, SYNERGISTIC TRANSCRIPTION MODULES AND USES THEREOF | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156795-A1 | METHODS FOR INHIBITION OF CELL PROLIFERATION, SYNERGISTIC TRANSCRIPTION MODULES AND USES THEREOF | MKI67, DCX, CTCF | ALDH1A1 4068/4885MAPT 4158/4885SMN1; SMN2 1942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.