SCHEMBL1503355

SCHEMBL1503355

CCCCCC(CF)OC(F)F

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.36
OPRM1 P35372 1/20 0.34
LMNA P02545 1/20 0.32
DNM1 Q05193 2/20 0.31
SMPD1 P17405 3/20 0.31
FDPS P14324 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24920243 0.86 MAPT (0.43) MAPTOPRM1LMNADNM1SMPD1
SCHEMBL14348243 0.81 DNM1 (0.36) LMNADNM1FDPS
SCHEMBL3793632 0.73 OPRM1 (0.46) OPRM1LMNADNM1SMPD1FDPS
SCHEMBL24920090 0.71 MAPT (0.42) MAPTOPRM1LMNADNM1SMPD1
SCHEMBL29143229 0.71 MAPT (0.42) MAPTOPRM1LMNADNM1SMPD1
SCHEMBL25141986 0.71 OPRM1 (0.41) MAPTOPRM1LMNADNM1
SCHEMBL1317403 0.71 TSHR (0.47) OPRM1LMNADNM1SMPD1FDPS
SCHEMBL8526142 0.71 TSHR (0.47) OPRM1LMNADNM1SMPD1FDPS
SCHEMBL1932239 0.71 TSHR (0.47) OPRM1LMNADNM1SMPD1FDPS
SCHEMBL4556813 0.71 TSHR (0.47) OPRM1LMNADNM1SMPD1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8449789-B2 Lubricant composition for refrigerating machines IDEMITSU KOSAN CO., LTD. (JP) 2013-05-28 US disclosed
US-8349205-B2 Lubricant composition for refrigerating machines IDEMITSU KOSAN CO., LTD. (JP) 2013-01-08 US disclosed
US-20110057146-A1 LUBRICANT COMPOSITION FOR REFRIGERATING MACHINES IDEMITSU KOSAN CO., LTD. (JP) 2011-03-10 US disclosed
US-20110049414-A1 LUBRICANT COMPOSITION FOR REFRIGERATING MACHINES IDEMITSU KOSAN CO., LTD. (JP) 2011-03-03 US disclosed
EP-2243818-A1 LUBRICANT COMPOSITION FOR REFRIGERATING MACHINES Idemitsu Kosan Co., Ltd. (JP) 2010-10-27 EP disclosed
EP-2243817-A1 LUBRICANT COMPOSITION FOR REFRIGERATING MACHINES Idemitsu Kosan Co., Ltd. (JP) 2010-10-27 EP disclosed