Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 5/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.36 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKMYT1 | Q99640 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25669241 | 0.87 | LMNA (0.39) | BTKGRM5BRD4BRD2BRD3 | |
| SCHEMBL14979428 | 0.83 | TGFBR1 (0.39) | BTKBRD4BRD2BRD3BAZ2B | |
| SCHEMBL18814738 | 0.78 | CYP2A6 (0.42) | GRM5MEN1KMT2AKDM4ENPC1 | |
| SCHEMBL15989883 | 0.77 | KDM4E (0.44) | BTKGRM5TGFBR1MEN1TP53 | |
| SCHEMBL15989832 | 0.77 | TGFBR1 (0.39) | BTKGRM5TGFBR1MEN1TP53 | |
| SCHEMBL21871827 | 0.76 | CYP3A4 (0.40) | MEN1KMT2AKDM4ECCR1CCR5 | |
| SCHEMBL15034456 | 0.75 | — | — | |
| SCHEMBL23873748 | 0.74 | CYP1A2 (0.49) | GRM5TGFBR1MEN1TP53PKM | |
| SCHEMBL27430944 | 0.74 | CYP1A2 (0.49) | GRM5TGFBR1MEN1TP53PKM | |
| SCHEMBL18333589 | 0.74 | GRM5 (0.40) | BTKGRM5TGFBR1MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3322693-B1 | A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME | ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) | 2020-02-12 | — | — | EP | disclosed |
| WO-2013085243-A1 | NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) | 2013-06-13 | — | — | WO | disclosed |