Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | EPM2A | O95278 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | CDC14A | Q9UNH5 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 3/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.37 |
| ▸ | WNT3A | P56704 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27388842 | 0.81 | CYP2A6 (0.46) | CYP2A6DYRK1ACDK9EPM2APTPRC | |
| SCHEMBL16152948 | 0.79 | CYP3A4 (0.56) | CYP2A6MAPK1TDP1CYP3A4DYRK1A | |
| SCHEMBL108863 | 0.75 | TDP1 (0.58) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL542795 | 0.73 | TDP1 (0.56) | CYP2A6MAPK1TDP1CYP3A4TRPA1 | |
| SCHEMBL29642672 | 0.73 | TDP1 (0.56) | CYP2A6MAPK1TDP1CYP3A4TRPA1 | |
| SCHEMBL9229837 | 0.71 | TDP1 (0.54) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL11227393 | 0.71 | TDP1 (0.54) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL96127 | 0.71 | CYP2A6 (0.66) | CYP2A6CYP3A4DYRK1ACDK9EPM2A | |
| SCHEMBL9229577 | 0.70 | MAPK1 (0.52) | MAPK1TDP1CYP3A4TRPA1TSHR | |
| SCHEMBL1169551 | 0.69 | MAPK1 (0.43) | MAPK1TDP1CYP3A4TRPA1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9518067-B2 | Trifluoroborate mass spectrometric tags | CellMosaic, Inc. (US) | 2016-12-13 | — | — | US | disclosed |
| US-9518067-B2 | Trifluoroborate mass spectrometric tags | CellMosaic, Inc. (US) | 2016-12-13 | — | — | US | disclosed |
| US-9518067-B2 | Trifluoroborate mass spectrometric tags | CellMosaic, Inc. (US) | 2016-12-13 | — | — | US | disclosed |
| US-20160333029-A1 | TRIFLUOROBORATE MASS SPECTROMETRIC TAGS | CELLMOSAIC INC (US) | 2016-11-17 | — | — | US | disclosed |
| US-20160333029-A1 | TRIFLUOROBORATE MASS SPECTROMETRIC TAGS | CELLMOSAIC INC (US) | 2016-11-17 | — | — | US | disclosed |
| US-20160333029-A1 | TRIFLUOROBORATE MASS SPECTROMETRIC TAGS | CELLMOSAIC INC (US) | 2016-11-17 | — | — | US | disclosed |
| US-9346833-B2 | Trifluoroborate mass spectrometric tags | CellMosaic, Inc. (US) | 2016-05-24 | — | — | US | disclosed |
| US-9346833-B2 | Trifluoroborate mass spectrometric tags | CellMosaic, Inc. (US) | 2016-05-24 | — | — | US | disclosed |
| US-20160052942-A1 | TRIFLUOROBORATE MASS SPECTROMETRIC TAGS | CELLMOSAIC INC (US) | 2016-02-25 | — | — | US | disclosed |
| WO-2014160739-A2 | TRIFLUOROBORATE MASS SPECTROMETRIC TAGS | CELLMOSAIC INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| WO-2014160739-A2 | TRIFLUOROBORATE MASS SPECTROMETRIC TAGS | CELLMOSAIC INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140235642-A1 | TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-20140235642-A1 | TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2014-08-21 | — | — | US | disclosed |
| US-8778941-B2 | TRPM8 antagonists and their use in treatments | AMGEN INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-8778941-B2 | TRPM8 antagonists and their use in treatments | AMGEN INC. (US) | 2014-07-15 | — | — | US | disclosed |
| US-20130158034-A1 | TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2013-06-20 | — | — | US | disclosed |
| US-20130158034-A1 | TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS | AMGEN INC. (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160052942-A1 | TRIFLUOROBORATE MASS SPECTROMETRIC TAGS | AFF4, BRS3, AFF2 | CYP2A6 1319/4885MAPK1 4114/4885TDP1 2701/4885 |
| US-20130158034-A1 | TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS | TRPM8, TRPM7, TRPM5 | CYP2A6 3052/4885MAPK1 1248/4885TDP1 2636/4885 |
| US-20140235642-A1 | TRPM8 ANTAGONISTS AND THEIR USE IN TREATMENTS | TRPM8, TRPM7, TRPM5 | CYP2A6 3052/4885MAPK1 1248/4885TDP1 2636/4885 |
| US-20160333029-A1 | TRIFLUOROBORATE MASS SPECTROMETRIC TAGS | AFF4, BRS3, AFF2 | CYP2A6 1319/4885MAPK1 4114/4885TDP1 2701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.