Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.32 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18531200 | 0.67 | PHGDH (0.37) | PHGDHMGLLCARM1PRMT6PRMT1 | |
| SCHEMBL24011271 | 0.67 | PHGDH (0.32) | PHGDHMGLLCARM1PRMT6PRMT1 | |
| SCHEMBL18383598 | 0.67 | ALDH1A1 (0.38) | PHGDHMGLLCARM1PRMT6PRMT1 | |
| SCHEMBL9830002 | 0.65 | — | — | |
| SCHEMBL16181361 | 0.65 | PHGDH (0.35) | PHGDHMGLLCARM1PRMT6PRMT1 | |
| SCHEMBL1629925 | 0.64 | PHGDH (0.42) | PHGDHMGLLCARM1PRMT6PRMT1 | |
| SCHEMBL11612677 | 0.64 | ALDH1A1 (0.41) | PHGDHMGLLACHEALDH1A1NPC1 | |
| SCHEMBL6015475 | 0.64 | ALDH1A1 (0.41) | PHGDHMGLLACHEALDH1A1NPC1 | |
| SCHEMBL31035961 | 0.64 | HPGD (0.35) | PHGDHMGLLCARM1PRMT6PRMT1 | |
| SCHEMBL12227760 | 0.64 | PHGDH (0.34) | PHGDHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013083775-A1 | NEW COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-06-13 | — | — | WO | disclosed |