Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Sulfosalicylic. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.68 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SERPINE1 | P05121 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 2/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfosalicylic SCHEMBL3291090 | 1.00 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| Sulfosalicylic SCHEMBL8592877 | 0.98 | ALDH1A1 (0.66) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| Sulfosalicylic SCHEMBL28400868 | 0.96 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| Sulfosalicylic SCHEMBL625073 | 0.96 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| Sulfosalicylic SCHEMBL28196640 | 0.96 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| Sulfosalicylic SCHEMBL30362977 | 0.96 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| Sulfosalicylic SCHEMBL8622539 | 0.96 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| Sulfosalicylic SCHEMBL6668124 | 0.96 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| Sulfosalicylic SCHEMBL1503559 | 0.96 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EHPGDLMNA | |
| Sulfosalicylic SCHEMBL11042773 | 0.96 | ALDH1A1 (0.68) | ALDH1A1HSD17B10KDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109137007-B | Environmentally friendly nickel electroplating compositions and methods | 罗门哈斯电子材料有限责任公司 | 2020-07-07 | — | — | CN | disclosed |
| EP-3431634-A1 | ENVIRONMENTALLY FRIENDLY NICKEL ELECTROPLATING COMPOSITIONS AND METHODS | Rohm and Haas Electronic Materials LLC (US) | 2019-01-23 | — | — | EP | disclosed |
| US-20180363157-A1 | ENVIRONMENTALLY FRIENDLY NICKEL ELECTROPLATING COMPOSITIONS AND METHODS | U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT | 2018-12-20 | — | — | US | disclosed |
| EP-1475232-B1 | Lithographic printing plate precursor, method for producing the same and method of lithographic printing | FUJIFILM CORP (JP) | 2011-08-17 | — | — | EP | disclosed |
| US-7906038-B2 | Aqueous polishing liquid and chemical mechanical polishing method | FUJIFILM CORPORATION (JP) | 2011-03-15 | — | — | US | disclosed |
| US-6824968-B2 | IMPROVED COLOR REPRODUCTION, AND PARTICULARLY TO A COLOR REVERSAL PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL WHICH IS SUPERIOR IN SKIN COLOR REPRODUCTION | FUJI PHOTO FILM CO., LTD. (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20040081927-A1 | Silver halide color reversal photographic light-sensitive material | FUJI PHOTO FILM CO., LTD | 2004-04-29 | — | — | US | disclosed |
| US-6682881-B2 | POLYOXYETHYLENE/POLYOXYPROPYLENE) COPOLYMER AS A SURFACE ACTIVE AGENT | FUJI PHOTO FILM CO., LTD. (JP) | 2004-01-27 | — | — | US | disclosed |
| US-6656673-B2 | Color photography | FUJI PHOTO FILM CO., LTD. (JP) | 2003-12-02 | — | — | US | disclosed |
| US-6645680-B2 | A lightsensitive silver halide emulsion layer comprising silver iodide grains capable of imparting interimage effects | FUJI PHOTO FILM CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-20030108826-A1 | Antifoaming agent composition for a silver halide photographic processing solution and process for processing a silver halide photographic material using same | FUJI PHOTO FILM CO., LTD. | 2003-06-12 | — | — | US | disclosed |
| US-20030091945-A1 | Silver halide color photographic material and method of reducing magenta stain | FUJI PHOTO FILM CO., LTD. | 2003-05-15 | — | — | US | disclosed |
| US-6548237-B2 | Pyrazolotriazole magenta coupler; color reversal | FUJI PHOTO FILM CO., LTD. (JP) | 2003-04-15 | — | — | US | disclosed |
| US-20030064329-A1 | Silver halide color reversal photographic material | FUJI PHOTO FILM CO., LTD. | 2003-04-03 | — | — | US | disclosed |
| EP-1241522-A1 | Processing method for silver halide color photographic material | Fuji Photo Film Co., Ltd. (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-6451517-B1 | Silver halide color photographic lightsensitive material and method for forming color image using the same | FUJI PHOTO FILM CO., LTD. (JP) | 2002-09-17 | — | — | US | disclosed |
| US-20020039709-A1 | Silver halide color photographic lightsensitive material and method of forming color image using the same | FUJIFILM CORPORATION (JP) | 2002-04-04 | — | — | US | disclosed |
| US-20020025497-A1 | Silver halide color photographic light-sensitive material and color image formation method using the same | FUJIFILM CORPORATION (JP) | 2002-02-28 | — | — | US | disclosed |
| US-6309471-B1 | Rapid removal of iodine stains | ECOLAB, INC. | 2001-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030108826-A1 | Antifoaming agent composition for a silver halide photographic processing solution and process for processing a silver halide photographic material using same | TTR, MAG, FGB | ALDH1A1 912/4885HSD17B10 1154/4885KDM4E 4084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.