Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 4/20 | 0.33 |
| ▸ | STK10 | O94804 | 2/20 | 0.32 |
| ▸ | SLK | Q9H2G2 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | APAF1 | O14727 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15039552 | 0.90 | PTGS1 (0.36) | IDO1TDO2PTGS1PTGS2GSK3B | |
| SCHEMBL16426662 | 0.81 | RAB9A (0.42) | MAPTALDH1A1LMNAMEN1APAF1 | |
| SCHEMBL16426672 | 0.81 | IDO1 (0.42) | IDO1TDO2PTGS1PTGS2GSK3B | |
| SCHEMBL16426665 | 0.79 | RAB9A (0.34) | MAPTMEN1APAF1NPC1POLB | |
| SCHEMBL15020067 | 0.76 | DNM1 (0.42) | IDO1TDO2PTGS1PTGS2GSK3B | |
| SCHEMBL15039580 | 0.76 | DNM1 (0.42) | IDO1TDO2PTGS1PTGS2GSK3B | |
| SCHEMBL15020065 | 0.76 | DNM1 (0.42) | IDO1TDO2PTGS1PTGS2GSK3B | |
| SCHEMBL15020486 | 0.75 | DNM1 (0.38) | IDO1TDO2PTGS1PTGS2GSK3B | |
| SCHEMBL15020488 | 0.75 | DNM1 (0.38) | IDO1TDO2PTGS1PTGS2GSK3B | |
| SCHEMBL16426675 | 0.75 | DNM1 (0.38) | IDO1TDO2PTGS1PTGS2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9439844-B2 | Tri-aromatic azomethine direct dyes comprising at least one unit derived from resorcinol, dyeing composition, method and use | L'OREAL (FR) | 2016-09-13 | — | — | US | disclosed |
| US-20150027483-A1 | TRI-AROMATIC AZOMETHINE DIRECT DYES COMPRISING AT LEAST ONE UNIT DERIVED FROM RESORCINOL, DYEING COMPOSITION, METHOD AND USE | L'OREAL (FR) | 2015-01-29 | — | — | US | disclosed |
| WO-2013087772-A1 | TRI-AROMATIC AZOMETHINE DIRECT DYES COMPRISING AT LEAST ONE UNIT DERIVED FROM RESORCINOL, DYEING COMPOSITION, METHOD AND USE | L'OREAL (FR) | 2013-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150027483-A1 | TRI-AROMATIC AZOMETHINE DIRECT DYES COMPRISING AT LEAST ONE UNIT DERIVED FROM RESORCINOL, DYEING COMPOSITION, METHOD AND USE | KRT18, IK, MKI67 | IDO1 264/4885TDO2 182/4885PTGS1 3385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.