Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 9/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | CSF3R | Q99062 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | C1S | P09871 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15037015 | 0.95 | PRSS1 (0.42) | PRSS1F10F2PLGPRSS2 | |
| SCHEMBL16419736 | 0.88 | L3MBTL1 (0.40) | PRSS1F10MTNR1AMTNR1BCYP1A1 | |
| SCHEMBL16419773 | 0.88 | L3MBTL1 (0.43) | PRSS1F10F2PLGPRSS2 | |
| SCHEMBL16419782 | 0.83 | CYP1A1 (0.48) | CSF3RCYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL15805902 | 0.83 | CYP1A1 (0.48) | CSF3RCYP1A1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL16419740 | 0.82 | L3MBTL1 (0.45) | PRSS1F10F2PLGPRSS2 | |
| SCHEMBL10064720 | 0.82 | F10 (0.53) | PRSS1F10F2PLGPRSS2 | |
| SCHEMBL16605484 | 0.82 | PRSS1 (0.44) | PRSS1F10F2PLGPRSS2 | |
| SCHEMBL16419774 | 0.81 | ABL1 (0.35) | PRSS1F10F2L3MBTL1 | |
| SCHEMBL16169701 | 0.79 | CSF3R (0.36) | CSF3RL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090185-A1 | CYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | POLYMEDIX, INC. (US) | 2013-06-20 | — | — | WO | disclosed |