Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | PLG | P00747 | 2/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | C1S | P09871 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | PROC | P04070 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | F9 | P00740 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16605484 | 0.87 | PRSS1 (0.44) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL15125587 | 0.87 | POLB (0.49) | F10PRSS1MTNR1AMTNR1BPLG | |
| SCHEMBL10031011 | 0.86 | F10 (0.48) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL15037015 | 0.86 | PRSS1 (0.42) | F10PRSS1MTNR1AMTNR1BF2 | |
| SCHEMBL17058978 | 0.86 | DRD2 (0.55) | F10PRSS1MTNR1AMTNR1BF2 | |
| SCHEMBL15244895 | 0.84 | PRSS1 (0.44) | F10PRSS1F2PLGPRSS2 | |
| SCHEMBL10310294 | 0.83 | MTNR1A (0.59) | F10PRSS1MTNR1AMTNR1BF2 | |
| SCHEMBL15036995 | 0.82 | PRSS1 (0.38) | F10PRSS1MTNR1AMTNR1BF2 | |
| Hydrochloric Acid SCHEMBL8207466 | 0.81 | MTNR1A (0.57) | F10PRSS1MTNR1AMTNR1BF2 | |
| SCHEMBL14165193 | 0.81 | F10 (0.41) | F10PRSS1MTNR1AMTNR1BF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077863-A1 | GUANIDINO-SUBSTITUTED BI-AND POLYPHENYLS AS SMALL MOLECULE CARRIERS | UCL BUSINESS PLC (GB) | 2012-03-29 | — | — | US | disclosed |
| WO-2010097604-A2 | NEW COMPOUNDS | UCL BUSINESS PLC (GB) | 2010-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077863-A1 | GUANIDINO-SUBSTITUTED BI-AND POLYPHENYLS AS SMALL MOLECULE CARRIERS | CFTR, GNB1, GMPS | F10 753/4885PRSS1 1267/4885MTNR1A 1911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.