Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPH1 | P17752 | 14/20 | 0.53 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15096518 | 0.93 | TPH1 (0.53) | TPH1SMPD1KDM4EGAAMAPT | |
| SCHEMBL15037265 | 0.92 | TPH1 (0.54) | TPH1SMPD1KDM4EGAAMAPT | |
| SCHEMBL15096517 | 0.92 | TPH1 (0.64) | TPH1SMPD1KDM4EMAPTLMNA | |
| SCHEMBL22448925 | 0.92 | TPH1 (0.64) | TPH1SMPD1KDM4EMAPTLMNA | |
| SCHEMBL15037368 | 0.91 | TPH1 (0.59) | TPH1SMPD1KDM4EMAPTLMNA | |
| SCHEMBL15037267 | 0.90 | TPH1 (0.52) | TPH1SMPD1KDM4EGAAMAPT | |
| SCHEMBL22449247 | 0.88 | S1PR4 (0.54) | TPH1KDM4EGAAMAPTLMNA | |
| SCHEMBL15037155 | 0.88 | S1PR4 (0.54) | TPH1KDM4EGAAMAPTLMNA | |
| SCHEMBL15037262 | 0.87 | TPH1 (0.61) | TPH1KDM4EGAAMAPTS1PR4 | |
| SCHEMBL15037108 | 0.87 | MAPT (0.48) | TPH1KDM4EGAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090454-A2 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2013-06-20 | — | — | WO | disclosed |