Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY1 | P47900 | 9/20 | 0.60 |
| ▸ | ENPP1 | P22413 | 3/20 | 0.60 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.60 |
| ▸ | P2RY11 | Q96G91 | 4/20 | 0.59 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.59 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.59 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.59 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.59 |
| ▸ | NT5E | P21589 | 2/20 | 0.59 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.56 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.55 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527226 | 0.92 | P2RY1 (0.69) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL14948878 | 0.92 | P2RY1 (0.69) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL29471281 | 0.92 | P2RY1 (0.69) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL1763062 | 0.92 | P2RY1 (0.69) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL15305340 | 0.90 | CA5A (0.67) | P2RY1ENPP1P2RY12P2RY11P2RX3 | |
| SCHEMBL15038284 | 0.89 | ADORA1 (0.62) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL14943009 | 0.85 | NT5E (0.59) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL31029199 | 0.85 | P2RY1 (0.68) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL20850061 | 0.84 | NT5E (0.71) | P2RY1ENPP1P2RY12P2RY11P2RX1 | |
| SCHEMBL18648315 | 0.84 | NT5E (0.71) | P2RY1ENPP1P2RY12P2RY11P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013090186-A1 | MODIFIED NUCLEIC ACIDS, AND ACUTE CARE USES THEREOF | modeRNA Therapeutics (US) | 2013-06-20 | — | — | WO | disclosed |