Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 5/20 | 0.59 |
| ▸ | P2RY1 | P47900 | 7/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.56 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.56 |
| ▸ | SRC | P12931 | 1/20 | 0.56 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | P2RY11 | Q96G91 | 2/20 | 0.55 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.55 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.55 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.54 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.54 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.53 |
| ▸ | MACROD2 | A1Z1Q3 | 1/20 | 0.53 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.53 |
| ▸ | MACROD1 | Q9BQ69 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15084445 | 0.89 | ADORA1 (0.62) | NT5EP2RY1P2RX3P2RY2P2RX1 | |
| SCHEMBL10048581 | 0.87 | P2RY1 (0.69) | NT5EP2RY1P2RX3P2RY2P2RX1 | |
| SCHEMBL10017676 | 0.87 | P2RY1 (0.69) | NT5EP2RY1P2RX3P2RY2P2RX1 | |
| SCHEMBL2619749 | 0.87 | P2RY1 (0.69) | NT5EP2RY1P2RX3P2RY2P2RX1 | |
| SCHEMBL14625239 | 0.87 | P2RY1 (0.69) | NT5EP2RY1P2RX3P2RY2P2RX1 | |
| 6-Thioguanylic Acid SCHEMBL15833214 | 0.86 | CA5A (0.69) | NT5EP2RY1P2RX3P2RY2SRC | |
| SCHEMBL15038285 | 0.85 | P2RY1 (0.60) | NT5EP2RY1P2RX3P2RX1P2RX4 | |
| SCHEMBL15084469 | 0.84 | P2RY1 (0.57) | NT5EP2RY1P2RX3P2RY2P2RX1 | |
| SCHEMBL15038284 | 0.84 | ADORA1 (0.62) | NT5EP2RY1P2RX3P2RX1P2RX4 | |
| SCHEMBL18950170 | 0.82 | ADORA3 (0.65) | NT5EP2RY1P2RX3P2RY2P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440812-B2 | Analogous compounds of 6-thioguanosine triphosphate, their use in medical fields and processes for their preparation | NOGRA PHARMA LIMITED (IE) | 2013-05-14 | — | — | US | disclosed |