SCHEMBL443217

SCHEMBL443217

Cc1ccc(C(=Cc2ccc(N(c3ccc(C)cc3)c3ccc(C=C(c4ccc(C)cc4)c4ccc(C)cc4)cc3)cc2)c2ccc(C)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.57
ESR1 P03372 2/20 0.50
ESR2 Q92731 1/20 0.50
MAPT P10636 4/20 0.48
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 3/20 0.48
HPGD P15428 1/20 0.48
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
GAA P10253 1/20 0.39
AKR1C3 P42330 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13508376 1.00 PTGS2 (0.57) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL139360 1.00 PTGS2 (0.57) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL18431952 0.95 PTGS2 (0.53) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL5937809 0.95 PTGS2 (0.53) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL5749657 0.95 PTGS2 (0.53) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL14526457 0.93 PTGS2 (0.61) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL10111285 0.93 PTGS2 (0.57) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL12144281 0.93 ESR1 (0.63) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL14570428 0.93 PTGS2 (0.61) PTGS2ESR1ESR2MAPTALDH1A1
SCHEMBL5937761 0.93 PTGS2 (0.61) PTGS2ESR1ESR2MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 146 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2141546-B1 Photoconductors containing Tris and Bis(enylaryl)arylamine XEROX CORP (US) 2013-05-22 EP claimed
US-20120208116-A1 BIS(ENYLARYL)ARYLAMINE CHARGE TRANSPORT LAYER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2012-08-16 US claimed
US-7981580-B2 Tris and bis(enylaryl)arylamine mixtures containing photoconductors XEROX CORPORATION (US) 2011-07-19 US claimed
US-7968262-B2 Bis(enylaryl)arylamine containing photoconductors XEROX CORPORATION (US) 2011-06-28 US claimed
US-20090325092-A1 BIS(ENYLARYL)ARYLAMINE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
US-20090325095-A1 TRIS AND BIS(ENYLARYL)ARYLAMINE MIXTURES CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2009-12-31 US claimed
US-11586119-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2023-02-21 US disclosed
US-20220413404-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2022-12-29 US disclosed
US-20220404724-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS Kyocera Document Solution Inc. (JP) 2022-12-22 US disclosed
US-20220397835-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2022-12-15 US disclosed
US-20220128913-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2022-04-28 US disclosed
US-11143976-B2 Photoconductor having interlayer for hole injection promotion FUJI ELECTRIC CO., LTD. (JP) 2021-10-12 US disclosed
US-11036151-B2 Electrophotographic photoreceptor, method for manufacturing same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2021-06-15 US disclosed
US-20090068577-A1 NAPHTHALENETETRACARBOXYLIC ACID DIIMIDE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR HAVING THE SAME RICOH COMPANY, LTD. (JP) 2009-03-12 US disclosed
US-20090004585-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND ELECTROPHOTOGRAPHIC APPARATUS YAMANASHI ELECTRONICS CO., LTD. (JP) 2009-01-01 US disclosed
US-20090004585-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND ELECTROPHOTOGRAPHIC APPARATUS YAMANASHI ELECTRONICS CO., LTD. (JP) 2009-01-01 US disclosed
US-20080298840-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-12-04 US disclosed
US-20080298840-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-12-04 US disclosed
US-20070231733-A1 IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2007-10-04 US disclosed
US-20070231733-A1 IMAGE FORMING APPARATUS AND IMAGE FORMING METHOD RICOH COMPANY, LTD. (JP) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220413404-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS PCNA, RPA3, PCBP1 PTGS2 3945/4885ESR1 1402/4885ESR2 2685/4885
US-20090068577-A1 NAPHTHALENETETRACARBOXYLIC ACID DIIMIDE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR HAVING THE SAME PAH, AHR, DECR1 PTGS2 1147/4885ESR1 717/4885ESR2 1255/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.