Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLLT1 | Q03111 | 1/20 | 0.46 |
| ▸ | PYGL | P06737 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | PYGM | P11217 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1504011 | 0.90 | EHMT2 (0.48) | PYGLPYGMSMYD3EHMT2F10 | |
| SCHEMBL1503874 | 0.90 | EHMT2 (0.48) | PYGLPYGMSMYD3EHMT2F10 | |
| SCHEMBL1503730 | 0.90 | EHMT2 (0.48) | PYGLPYGMSMYD3EHMT2F10 | |
| SCHEMBL2943145 | 0.79 | MLLT1 (0.51) | MLLT1PYGLMEN1KMT2AGHSR | |
| SCHEMBL4265020 | 0.78 | MLLT1 (0.51) | MLLT1PYGLMEN1KMT2AGHSR | |
| SCHEMBL12035676 | 0.78 | MLLT1 (0.51) | MLLT1PYGLMEN1KMT2AGHSR | |
| SCHEMBL765158 | 0.78 | MLLT1 (0.47) | MLLT1PYGLMEN1KMT2AGHSR | |
| SCHEMBL208111 | 0.76 | MLLT1 (0.48) | MLLT1PYGLMEN1KMT2AGHSR | |
| SCHEMBL4269561 | 0.76 | F10 (0.60) | MLLT1PYGLGHSRPYGMF10 | |
| SCHEMBL1503975 | 0.72 | CPB1 (0.44) | KMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2343290-A1 | Diamine derivatives as factor X inhibitors | Daiichi Sankyo Company, Limited (JP) | 2011-07-13 | — | — | EP | disclosed |
| US-20110077266-A1 | Diamine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-31 | — | — | US | disclosed |
| US-20050119486-A1 | Diamine derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119486-A1 | Diamine derivatives | C9, C1S, C1R | MLLT1 755/4885PYGL 3803/4885MEN1 457/4885 |
| US-20110077266-A1 | Diamine Derivatives | F2, TFPI, F3 | MLLT1 1088/4885PYGL 1509/4885MEN1 1094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.