Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB1 | P15086 | 2/20 | 0.44 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28376797 | 0.85 | CPB1 (0.47) | CPB1SYKPDE4BALDH1A1GAA | |
| SCHEMBL28380419 | 0.85 | CPB1 (0.47) | CPB1SYKPDE4BALDH1A1GAA | |
| SCHEMBL3563686 | 0.81 | KMT2A (0.56) | CPB1SYKPDE4BALDH1A1GAA | |
| SCHEMBL4033681 | 0.81 | CPB1 (0.54) | CPB1SYKPDE4BALDH1A1GAA | |
| SCHEMBL742036 | 0.77 | KMT2A (0.44) | PDE4BKMT2AL3MBTL1KDM1AMAOB | |
| SCHEMBL22617362 | 0.77 | CPB1 (0.54) | CPB1SYKPDE4BALDH1A1GAA | |
| SCHEMBL740804 | 0.77 | BTK (0.37) | ALDH1A1GAAKMT2AL3MBTL1KDM1A | |
| SCHEMBL5511308 | 0.77 | BTK (0.37) | ALDH1A1GAAKMT2AL3MBTL1KDM1A | |
| SCHEMBL1504585 | 0.77 | BTK (0.37) | ALDH1A1GAAKMT2AL3MBTL1KDM1A | |
| SCHEMBL3944460 | 0.77 | ALDH1A1 (0.69) | CPB1SYKALDH1A1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110077266-A1 | Diamine Derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-31 | — | — | US | disclosed |
| US-20100093785-A1 | DIAMINE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2010-04-15 | — | — | US | disclosed |
| US-20050119486-A1 | Diamine derivatives | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100093785-A1 | DIAMINE DERIVATIVES | C9, C1S, C1R | CPB1 3417/4885SYK 1675/4885PDE4B 4679/4885 |
| US-20050119486-A1 | Diamine derivatives | C9, C1S, C1R | CPB1 3108/4885SYK 2089/4885PDE4B 4705/4885 |
| US-20110077266-A1 | Diamine Derivatives | F2, TFPI, F3 | CPB1 136/4885SYK 1228/4885PDE4B 862/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.