Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.31 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17253298 | 0.95 | ALDH1A1 (0.35) | MAPTTDP1L3MBTL1ALDH1A1HTT | |
| SCHEMBL15020117 | 0.95 | ALDH1A1 (0.35) | MAPTTDP1L3MBTL1ALDH1A1HTT | |
| SCHEMBL15020118 | 0.95 | ALDH1A1 (0.35) | MAPTTDP1L3MBTL1ALDH1A1HTT | |
| SCHEMBL15020129 | 0.90 | ALDH1A1 (0.37) | MAPTTDP1L3MBTL1ALDH1A1HTT | |
| SCHEMBL15020128 | 0.90 | ALDH1A1 (0.37) | MAPTTDP1L3MBTL1ALDH1A1HTT | |
| SCHEMBL17253269 | 0.90 | ALDH1A1 (0.37) | MAPTTDP1L3MBTL1ALDH1A1HTT | |
| SCHEMBL15039564 | 0.85 | APAF1 (0.39) | MAPTTDP1L3MBTL1ALDH1A1HTT | |
| SCHEMBL15019813 | 0.85 | APAF1 (0.39) | MAPTTDP1L3MBTL1ALDH1A1HTT | |
| SCHEMBL15039548 | 0.85 | MAPT (0.41) | MAPTTDP1L3MBTL1ALDH1A1HTT | |
| SCHEMBL15019814 | 0.85 | APAF1 (0.39) | MAPTTDP1L3MBTL1ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013087768-A1 | TRIAROMATIC AZOMETHINE DIRECT DYES, DYE COMPOSITION COMPRISING AT LEAST ONE SUCH DYE, METHOD OF IMPLEMENTATION AND USE | L'OREAL (FR) | 2013-06-20 | — | — | WO | disclosed |