Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 20/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10056024 | 0.86 | P2RX3 (0.66) | P2RX3 | |
| SCHEMBL10055370 | 0.83 | P2RX3 (0.69) | P2RX3 | |
| SCHEMBL12045888 | 0.74 | P2RX3 (0.68) | P2RX3 | |
| SCHEMBL10056259 | 0.74 | P2RX3 (0.66) | P2RX3 | |
| SCHEMBL10056023 | 0.72 | PROKR1 (0.63) | P2RX3 | |
| SCHEMBL12045890 | 0.72 | P2RX3 (0.68) | P2RX3 | |
| SCHEMBL9983197 | 0.71 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL12046515 | 0.71 | P2RX3 (1.00) | P2RX3 | |
| SCHEMBL5364326 | 0.70 | DRD2 (0.64) | P2RX3 | |
| SCHEMBL8280023 | 0.69 | PROKR1 (0.63) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604595-B1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | SHIONOGI & CO (JP) | 2016-03-16 | — | — | EP | disclosed |
| EP-2604595-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | Shionogi&Co., Ltd. (JP) | 2013-06-19 | — | — | EP | disclosed |