SCHEMBL150405

SCHEMBL150405

O=CC[Mg]Cc1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADH1B P00325 1/20 0.40
ADH1C P00326 1/20 0.40
ADH1A P07327 1/20 0.40
ADH7 P40394 1/20 0.40
ALDH1A1 P00352 4/20 0.37
MAOB P27338 1/20 0.37
HPGD P15428 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
CASP1 P29466 1/20 0.37
HSD17B10 Q99714 1/20 0.37
EPHX1 P07099 1/20 0.36
CALM1 P0DP23 1/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
EPHX2 P34913 1/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
AKR1B1 P15121 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8599727 0.77 ALDH1A1 (0.37) ADH1BADH1CADH1AADH7ALDH1A1
SCHEMBL150474 0.77 ALDH1A1 (0.50) ALDH1A1MAOBHPGDALOX15ALOX12
Hydrochloric Acid SCHEMBL29262829 0.75 ALDH1A1 (0.48) ALDH1A1MAOBHPGDALOX15ALOX12
SCHEMBL8602897 0.74 MAOB (0.39) ALDH1A1MAOBHPGDALOX15ALOX12
SCHEMBL8602900 0.74 MAOB (0.39) ALDH1A1MAOBHPGDALOX15ALOX12
SCHEMBL6957629 0.71 ADH1B (0.43) ADH1BADH1CADH1AADH7ALDH1A1
Phenylacetaldehyde SCHEMBL18972 0.69
Phenylacetaldehyde SCHEMBL31402006 0.69
Phenylacetaldehyde SCHEMBL3319438 0.69 MAOB (0.63) ADH1BADH1CADH1AADH7ALDH1A1
Phenylacetaldehyde SCHEMBL31725265 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 403 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3969490-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND TIRE COMPONENTS BRIDGESTONE CORP (JP) 2026-03-25 EP disclosed
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-12-25 US disclosed
US-12479935-B2 Polymerization processes for the production of cis-1,4-polydienes BRIDGESTONE CORPORATION (JP) 2025-11-25 US disclosed
US-12410263-B2 Modified high-Cis polybutadiene polymer, related methods and rubber compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-12371516-B2 Aged lanthanide-based catalyst systems and their use in the preparation of cis-1,4-polydienes BRIDGESTONE CORPORATION (JP) 2025-07-29 US disclosed
US-12264232-B2 Modified high-cis polybutadiene polymer, related methods and tire components BRIDGESTONE CORPORATION (JP) 2025-04-01 US disclosed
US-20250066516-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2025-02-27 US disclosed
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP disclosed
US-12168705-B2 Modified high cis polydiene polymer, related methods and rubber compositions BRIDGESTONE CORPORATION (JP) 2024-12-17 US disclosed
EP-4457250-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME Bridgestone Corporation (JP) 2024-11-06 EP disclosed
WO-2002066525-A1 CHROMIUM-BASED CATALYST COMPOSITION BRIDGESTONE CORPORATION (JP) 2002-08-29 WO disclosed
US-20020115558-A1 CHROMIUM-BASED CATALYST COMPOSITION FOR PRODUCING CONJUGATED DIENE POLYMERS BRIDGESTONE CORP. 2002-08-22 US disclosed
US-20020037967-A1 Process for producing blends of syndiotactic 1,2-polybutadiene and rubbery elastomers with a chromium-based catalyst system BRIDGESTONE CORPORATION (JP) 2002-03-28 US disclosed
US-6340751-B1 REACTION OF IMIDAZOLONE WITH AMIDE AND MAGNESIUM COMPOUND TAKASAGO INTERNATIONAL CORPORATION (JP) 2002-01-22 US disclosed
US-6320004-B1 FORMED BY COMBINING (A) A IRON-CONTAINING COMPOUND; (B) AN ORGANOMAGNESIUM COMPOUND; AND (C) A SILYL PHOSPHONATE; POLYMERIZING CONJUGATED DIENE MONOMERS BRIDGESTONE CORPORATION (JP) 2001-11-20 US disclosed
WO-2001079309-A2 USE OF A Cr- OR Mo-BASED CATALYST SYSTEM TO PRODUCE BLENDS OF SYNDIOTACTIC 1,2-POLYBUTADIENE AND RUBBERY ELASTOMERS BRIDGESTONE CORPORATION (JP) 2001-10-25 WO disclosed
US-6291591-B1 PROVIDING MIXTURE OF RUBBER CEMENT AND 1,3-BUTADIENE; POLYMERIZING 1,3-BUTADIENE BY USING A CATALYST WHICH IS COMBINATION OF OR THE REACTION PRODUCT OF CHROMIUM COMPOUND, HYDROGEN PHOSPHITE, ORGANOMAGNESIUM COMPOUND BRIDGESTONE CORPORATION (JP) 2001-09-18 US disclosed
WO-2001049755-A1 IRON-BASED CATALYST FOR PRODUCING BINARY Cis-1,4-/1,2-POLYBUTADIENE BRIDGESTONE CORPORATION (JP) 2001-07-12 WO disclosed
US-6160063-A Iron-based catalyst for producing binary cis-1,4-/1,2-polybutadiene BRIDGESTONE CORPORATION (JP) 2000-12-12 US disclosed
EP-0974582-A1 Process for the preparation of 4-substituted azetidinone derivatives Takasago International Corporation (JP) 2000-01-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS MALT1, INO80C, RTCB ADH1B 1779/4885ADH1C 6/4885ADH1A 39/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.