Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | EYA2 | O00167 | 1/20 | 0.56 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | ACE | P12821 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 3/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | DRD1 | P21728 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3926050 | 0.88 | TDP1 (0.65) | TDP1EYA2APPACEBLM | |
| SCHEMBL3930821 | 0.86 | TDP1 (0.62) | TDP1EYA2APPACEBLM | |
| SCHEMBL890300 | 0.80 | MAPT (0.50) | BLMCYP2C19CHRM2TSHRCYP2D6 | |
| SCHEMBL2471304 | 0.74 | TDP1 (0.59) | TDP1EYA2APPACEBLM | |
| SCHEMBL9525485 | 0.74 | CYP2D6 (0.50) | TDP1BLMCYP2C19LMNATSHR | |
| Edetic Acid SCHEMBL1373 | 0.74 | TDP1 (1.00) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL8607480 | 0.74 | TDP1 (1.00) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL15136 | 0.74 | TDP1 (1.00) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL8624198 | 0.74 | TDP1 (1.00) | TDP1EYA2APPACEBLM | |
| Edetic Acid SCHEMBL16714076 | 0.74 | TDP1 (1.00) | TDP1EYA2APPACEBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040126344-A1 | Compositions having glycolipid to lighten skin and alter post-inflammatory hyperpigmentation | AVON PRODUCTS, INC. | 2004-07-01 | — | — | US | claimed |
| US-12156832-B2 | Method, and system for multi-layer cosmetic pads and use thereof | ELC MANAGEMENT LLC (US) | 2024-12-03 | — | — | US | disclosed |
| EP-4087441-A1 | METHOD, AND SYSTEM FOR MULTI-LAYER COSMETIC PADS AND USE THEREOF | ELC Management LLC (US) | 2022-11-16 | — | — | EP | disclosed |
| WO-2021141926-A1 | METHOD, AND SYSTEM FOR MULTI-LAYER COSMETIC PADS AND USE THEREOF | ELC MANAGEMENT LLC (US) | 2021-07-15 | — | — | WO | disclosed |
| US-20210205125-A1 | Method, And System For Multi-Layer Cosmetic Pads and Use Thereof | ELC MANAGEMENT LLC | 2021-07-08 | — | — | US | disclosed |
| EP-2969030-B1 | A TOPICAL LIGHTENING COMPOSITION AND METHODS OF USE THEREOF | AVON PROD INC (US) | 2021-01-13 | — | — | EP | disclosed |
| US-10117821-B2 | Topical lightening composition and methods of use thereof | AVON PRODUCTS, INC. (US) | 2018-11-06 | — | — | US | disclosed |
| EP-2473183-B1 | COSMETIC USES OF MODIFIED STRESSED YEAST EXTRACTS AND RELATED COMPOSITIONS | AVON PROD INC (US) | 2018-06-27 | — | — | EP | disclosed |
| EP-3148651-A1 | TOPICAL LIGHTENING COMPOSITION AND METHODS OF USE THEREOF | Avon Products, Inc. (US) | 2017-04-05 | — | — | EP | disclosed |
| EP-2890359-B1 | DICKKOPF-1 EXPRESSION MODULATING COMPOSITIONS AND USES THEREOF | AVON PROD INC (US) | 2016-10-05 | — | — | EP | disclosed |
| US-20140065086-A1 | Dickkopf-1 Expression Modulating Compositions and Uses Thereof | AVON PRODUCTS, INC. (US) | 2014-03-06 | — | — | US | disclosed |
| US-8575106-B2 | Cosmetic uses of modified stressed yeast extracts and related compositions | AVON PRODUCTS, INC. (US) | 2013-11-05 | — | — | US | disclosed |
| EP-2473183-A2 | COSMETIC USES OF MODIFIED STRESSED YEAST EXTRACTS AND RELATED COMPOSITIONS | Avon Products, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |
| EP-1572223-B1 | USE OF ACTIVE EXTRACTS TO IMPROVE THE APPEARANCE OF SKIN, LIPS, HAIR AND/OR NAILS | AVON PROD INC (US) | 2011-06-22 | — | — | EP | disclosed |
| US-20110052517-A1 | Cosmetic Uses of Modified Stressed Yeast Extracts and Related Compositions | Avon Place (US) | 2011-03-03 | — | — | US | disclosed |
| WO-2011025635-A2 | COSMETIC USES OF MODIFIED STRESSED YEAST EXTRACTS AND RELATED COMPOSITIONS | AVON PRODUCTS, INC. (US) | 2011-03-03 | — | — | WO | disclosed |
| US-7189419-B2 | Use of active extracts to lighten skin, lips, hair, and/or nails | AVON PRODUCTS, INC. (US) | 2007-03-13 | — | — | US | disclosed |
| US-20060013782-A1 | Use of active extracts to improve the appearance of skin, lips, hair and/or nails | AVON PRODUCTS, INC. | 2006-01-19 | — | — | US | disclosed |
| US-20040126344-A1 | Compositions having glycolipid to lighten skin and alter post-inflammatory hyperpigmentation | AVON PRODUCTS, INC. | 2004-07-01 | — | — | US | disclosed |
| US-20040115146-A1 | Use of active extracts to lighten skin, lips, hair and/or nails | AVON PRODUCTS, INC. | 2004-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10117821-B2 | Topical lightening composition and methods of use thereof | TYR, CUTA, TUBA1A | TDP1 2436/4885EYA2 44/4885APP 3411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.