Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24266810 | 0.90 | L3MBTL1 (0.44) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL24266601 | 0.90 | ALDH1A1 (0.41) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL22277120 | 0.89 | KDM4E (0.51) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL24266258 | 0.86 | ALDH1A1 (0.47) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL22096973 | 0.85 | KDM4E (0.43) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL24275436 | 0.84 | MAPT (0.36) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL24275122 | 0.84 | MAPT (0.36) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL24266908 | 0.84 | ALDH1A1 (0.45) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL22880551 | 0.82 | L3MBTL1 (0.43) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 | |
| SCHEMBL22880226 | 0.82 | L3MBTL1 (0.43) | ALDH1A1MAPTRAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140358198-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20140358198-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |