SCHEMBL15041103

SCHEMBL15041103

Cc1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4ccc(N(c5ccccc5)c5ccccc5)cc4)cc3C)cc2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 3/20 0.37
TDP1 Q9NUW8 3/20 0.37
L3MBTL1 Q9Y468 3/20 0.37
CYP2C19 P33261 2/20 0.37
MAPT P10636 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
APP P05067 2/20 0.37
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
RAB9A P51151 4/20 0.33
NPC1 O15118 3/20 0.33
HPGD P15428 2/20 0.33
MCL1 Q07820 1/20 0.33
CA12 O43570 1/20 0.33
CA9 Q16790 1/20 0.33
FLT3 P36888 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13136846 0.98 CYP2C19 (0.37) ALDH1A1KDM4ETDP1L3MBTL1CYP2C19
SCHEMBL7764386 0.97 CYP2C19 (0.38) ALDH1A1KDM4ETDP1L3MBTL1CYP2C19
SCHEMBL14732535 0.97 CYP2C19 (0.38) ALDH1A1KDM4ETDP1L3MBTL1CYP2C19
SCHEMBL7613942 0.95 MEN1 (0.38) ALDH1A1KDM4ETDP1L3MBTL1CYP2C19
SCHEMBL14732542 0.95 MEN1 (0.38) ALDH1A1KDM4ETDP1L3MBTL1CYP2C19
SCHEMBL12533878 0.95 MEN1 (0.38) ALDH1A1KDM4ETDP1L3MBTL1CYP2C19
SCHEMBL19826255 0.95 MEN1 (0.38) ALDH1A1KDM4ETDP1L3MBTL1CYP2C19
SCHEMBL14106797 0.95 ALDH1A1 (0.41) ALDH1A1KDM4ETDP1L3MBTL1CYP2C19
SCHEMBL8642454 0.95 ALDH1A1 (0.41) ALDH1A1KDM4ETDP1L3MBTL1CYP2C19
SCHEMBL13929906 0.93 ALDH1A1 (0.37) ALDH1A1KDM4ETDP1L3MBTL1CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2321376-B1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORP (US) 2013-06-19 EP disclosed