Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | SPHK1 | Q9NYA1 | 11/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SPHK2 | Q9NRA0 | 7/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29418 | 0.79 | ESR2 (0.57) | ESR2SPHK1ESR1CYP3A4CYP2C9 | |
| SCHEMBL11196166 | 0.78 | ESR2 (0.77) | ESR2SPHK1ESR1CYP3A4CYP2C9 | |
| SCHEMBL31330 | 0.77 | ESR2 (0.46) | ESR2SPHK1ACHETP53 | |
| SCHEMBL24554063 | 0.76 | ESR2 (0.45) | ESR2SPHK1ACHESPHK2TP53 | |
| SCHEMBL11274428 | 0.76 | ESR2 (0.45) | ESR2SPHK1ACHESPHK2TP53 | |
| SCHEMBL14473176 | 0.76 | ESR2 (0.57) | ESR2SPHK1ESR1CYP3A4CYP2C9 | |
| SCHEMBL13615716 | 0.76 | ESR2 (0.62) | ESR2SPHK1ESR1CYP3A4CYP2C9 | |
| SCHEMBL15043506 | 0.76 | ESR2 (0.57) | ESR2ESR1CYP3A4CYP2C9 | |
| SCHEMBL17186386 | 0.76 | SPHK1 (0.40) | ESR2SPHK1ESR1CYP3A4CYP2C9 | |
| SCHEMBL15449220 | 0.76 | ESR2 (0.57) | ESR2SPHK1ESR1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |