Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.35 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.35 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 9/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18721979 | 0.86 | CTSC (0.45) | CTSC | |
| SCHEMBL8763089 | 0.77 | ESR2 (0.42) | ESR2 | |
| SCHEMBL10900107 | 0.77 | ESR2 (0.52) | ESR2GRIA1GRIA2GRIA3SPHK1 | |
| SCHEMBL15043502 | 0.77 | ESR2 (0.52) | ESR2SPHK1ACHETP53 | |
| SCHEMBL10900100 | 0.77 | ESR2 (0.52) | ESR2GRIA1GRIA2GRIA3SPHK1 | |
| SCHEMBL13615716 | 0.74 | ESR2 (0.62) | ESR2SPHK1 | |
| SCHEMBL24554063 | 0.74 | ESR2 (0.45) | ESR2CTSCSPHK1ACACBACHE | |
| SCHEMBL11274428 | 0.74 | ESR2 (0.45) | ESR2SPHK1ACHETP53 | |
| SCHEMBL10900088 | 0.73 | ESR2 (0.47) | ESR2SPHK1 | |
| SCHEMBL10900086 | 0.73 | ESR2 (0.47) | ESR2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |
| WO-2012025182-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |
| EP-2423294-A1 | Switch element comprising a liquid-crystalline medium | Merck Patent GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |