Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | CTSC | P53634 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630169 | 0.96 | TRPV4 (0.34) | TRPV4CHRM2CHRM1CHRM5MAOB | |
| SCHEMBL9630172 | 0.96 | TRPV4 (0.34) | TRPV4CHRM2CHRM1CHRM5MAOB | |
| SCHEMBL9630094 | 0.88 | TRPV4 (0.37) | TRPV4CHRM2CHRM1CHRM5MAOB | |
| SCHEMBL9630101 | 0.88 | TRPV4 (0.37) | TRPV4CHRM2CHRM1CHRM5MAOB | |
| SCHEMBL9347180 | 0.86 | HRH3 (0.40) | TRPV4CHRM2CHRM1CHRM5MAOB | |
| SCHEMBL9347174 | 0.86 | HRH3 (0.40) | TRPV4CHRM2CHRM1CHRM5MAOB | |
| SCHEMBL18722116 | 0.84 | DAO (0.39) | TRPV4MAOBMAOAHRH3CTSS | |
| SCHEMBL9061373 | 0.84 | TRPV4 (0.34) | TRPV4CHRM2CHRM1CHRM5MAOB | |
| SCHEMBL9061364 | 0.84 | TRPV4 (0.34) | TRPV4CHRM2CHRM1CHRM5MAOB | |
| SCHEMBL9631070 | 0.84 | TRPV4 (0.34) | TRPV4CHRM2CHRM1CHRM5MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |